Lithographically patterned molecularly imprinted polymer for gravimetric detection of trace atrazine

Yang, Jin Chul; Shin, Hoon−Kyu; Hong, Suck Won; Park, Jin Young

doi:10.1016/j.snb.2015.04.079

Cited by 30 publications

(25 citation statements)

References 30 publications

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“…The imprinting process is performed in the presence of the target as a whole virus particle, a single protein, or epitope to generate specific receptor/binding sites that have a high affinity for a targeted virus [92][93][94][95][96][97]. Such materials can be fabricated by different techniques (e.g., electropolymerization, microcontact printing, molding, and self-assembly), thus widening their applicability [98][99][100][101]. VIT has been used for the electrochemical detection of Zika virus using on-surface imprinted polymers and graphene oxide composites [102].…”

Section: Point-of-care and Standalone Biosensing Devicesmentioning

confidence: 99%

Point-of-Care Diagnostics of COVID-19: From Current Work to Future Perspectives

Hussein

Hassan

Chino

et al. 2020

Sensors

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Coronaviruses have received global concern since 2003, when an outbreak caused by SARS-CoV emerged in China. Later on, in 2012, the Middle-East respiratory syndrome spread in Saudi Arabia, caused by MERS-CoV. Currently, the global crisis is caused by the pandemic SARS-CoV-2, which belongs to the same lineage of SARS-CoV. In response to the urgent need of diagnostic tools, several lab-based and biosensing techniques have been proposed so far. Five main areas have been individuated and discussed in terms of their strengths and weaknesses. The cell-culture detection and the microneutralization tests are still considered highly reliable methods. The genetic screening, featuring the well-established Real-time polymerase chain reaction (RT-PCR), represents the gold standard for virus detection in nasopharyngeal swabs. On the other side, immunoassays were developed, either by screening/antigen recognition of IgM/IgG or by detecting the whole virus, in blood and sera. Next, proteomic mass-spectrometry (MS)-based methodologies have also been proposed for the analysis of swab samples. Finally, virus-biosensing devices were efficiently designed. Both electrochemical immunosensors and eye-based technologies have been described, showing detection times lower than 10 min after swab introduction. Alternative to swab-based techniques, lateral flow point-of-care immunoassays are already commercially available for the analysis of blood samples. Such biosensing devices hold the advantage of being portable for on-site testing in hospitals, airports, and hotspots, virtually without any sample treatment or complicated lab precautions.

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Section: Point-of-care and Standalone Biosensing Devicesmentioning

confidence: 99%

Point-of-Care Diagnostics of COVID-19: From Current Work to Future Perspectives

Hussein

Hassan

Chino

et al. 2020

Sensors

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“…In surface imprinting ( Figure 2), a certain degree of protein stabilization is achieved by using oriented immobilization of template [35][36][37][38]. Typically, template is immobilized onto the surface of a sacrificial material such as SiO 2 , which is immersed in the monomer mixture during polymerization.…”

Section: Imprinting Of Proteinsmentioning

confidence: 99%

“…Sci. 2019, 20, x FOR PEER REVIEW 5 Schematic representations of protocols used in surface imprinting; (a) imprinting immobilized template on silica surfaces, reproduced from [35] with permission; (b) imprinting by surface grafting, reproduced from [36] with permission; and (c) soft lithography and UV initiated polymerization, adapted from[37] with permission.…”

mentioning

confidence: 99%

Strategies for Molecular Imprinting and the Evolution of MIP Nanoparticles as Plastic Antibodies—Synthesis and Applications

Refaat

Aggour

Farghali

et al. 2019

IJMS

145

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Materials that can mimic the molecular recognition-based functions found in biology are a significant goal for science and technology. Molecular imprinting is a technology that addresses this challenge by providing polymeric materials with antibody-like recognition characteristics. Recently, significant progress has been achieved in solving many of the practical problems traditionally associated with molecularly imprinted polymers (MIPs), such as difficulties with imprinting of proteins, poor compatibility with aqueous environments, template leakage, and the presence of heterogeneous populations of binding sites in the polymers that contribute to high levels of non-specific binding. This success is closely related to the technology-driven shift in MIP research from traditional bulk polymer formats into the nanomaterial domain. The aim of this article is to throw light on recent developments in this field and to present a critical discussion of the current state of molecular imprinting and its potential in real world applications.

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“…Once adding trace amounts of atrazine into the mixture solution, the sensor response showed 94% recovery of the original sensing response appeared in atrazine solution. Therefore, the lithographic approach to MIP sensing system provides rapid and ultra-sensitive detection in a selective way [ 29 ].…”

Section: Molecular Imprinting Techniquesmentioning

confidence: 99%

“…( 4 ) Following de-molding, the patterned MIP films were dried at 60 °C. ( 5 ) In the last step, template molecule (atrazine) was removed from the surface (reproduced from [ 29 ] with permission).…”

Section: Figurementioning

confidence: 99%

Molecular Imprinting Techniques Used for the Preparation of Biosensors

Ertürk

Mattìasson

2017

Sensors

219

100

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Molecular imprinting is the technology of creating artificial recognition sites in polymeric matrices which are complementary to the template in their size, shape and spatial arrangement of the functional groups. Molecularly imprinted polymers (MIPs) and their incorporation with various transducer platforms are among the most promising approaches for detection of several analytes. There are a variety of molecular imprinting techniques used for the preparation of biomimetic sensors including bulk imprinting, surface imprinting (soft lithography, template immobilization, grafting, emulsion polymerization) and epitope imprinting. This chapter presents an overview of all of these techniques with examples from particular publications.

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Lithographically patterned molecularly imprinted polymer for gravimetric detection of trace atrazine

Cited by 30 publications

References 30 publications

Point-of-Care Diagnostics of COVID-19: From Current Work to Future Perspectives

Point-of-Care Diagnostics of COVID-19: From Current Work to Future Perspectives

Strategies for Molecular Imprinting and the Evolution of MIP Nanoparticles as Plastic Antibodies—Synthesis and Applications

Molecular Imprinting Techniques Used for the Preparation of Biosensors

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