Live-birth rates in very poor prognosis patients, who are defined as poor responders under the Bologna criteria, with nonelective single embryo, two-embryo, and three or more embryos transferred

Abstract

Very poor prognosis patients can still achieve acceptable pregnancy rates at least till their mid-40s if they reach ET. The degree to which egg donation is emphasized as the only treatment option in such patients, therefore, requires reconsideration. Above age 42, at least two, and preferably three embryos, are however required to exceed futility, as defined by ASRM.

Systemic Inflammation and Autoimmunity in Women with Chronic Endometritis

“…Our center serves primarily poor prognosis patients of advanced reproductive age and reproductive treatment history characterized by multiple prior in vitro fertilization (IVF) failures . For the purposes of this study, RPL was defined as two or more consecutive pregnancy losses before 10 weeks of gestation.…”

With low ovarian reserve, Highly Individualized Egg Retrieval (HIER) improves IVF results by avoiding premature luteinization

“…Pregnancy and live birth rates in association with in vitro fertilization (IVF) decline slowly and persistantly with advancing female age [ 1 ]. After age 43, this gradual decline, however, significantly accellerates [ 2 ]. Based on national outcome reporting, our center serves a disproportionally older patient population in comparison to all other U.S. IVF centers [ 1 ].…”

Modification of ovarian stimulation schemes: Indications and efficiency

“…Прекрасные результаты! Но вот данные N. Gleicher [8] показали, что при использовании того же протокола в сравнении со стандартной стимуляцией: ЧНБ на перенос эмбрионов составила 21,4 и 50%, криоконсервация -0 и 60%, ЧНБ на криоперенос -0 и 28,5%, кумулятивная ЧНБ -21,4 и 64,3%. Результаты резко отличаются от приведенных ранее!…”

“…Стимуляция яичников позволяет получить достаточное количество ооцитов (8)(9)(10)(11)(12)(13)(14)(15), выбрать лучшие из них, оплодотворить и получить 4-6 бластоцист, перенести 1-2 бластоцисты, оставшиеся законсервировать. Такова классическая программа ЭКО, при которой кумулятивная частота наступления беременности с учетом криопереносов, действительно, может достигать 60% на пациентку.…”