Liver Fluke

Mitchell, Gillian

doi:10.1002/9780470753316.ch28

Cited by 7 publications

(8 citation statements)

References 4 publications

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“…Permanent habitats include banks of ditches, streams and the edges of small ponds. However, following heavy rainfall or flooding, temporary habitats may include wheel ruts and rain ponds [ 7 ].…”

Section: Life Cyclementioning

confidence: 99%

“…Liver fluke infection affects both productivity and welfare, and represents a considerable economic burden on livestock farming, with subclinical losses contributing a large proportion of the cost, including reduced milk yield, fertility and growth rates [ 5 , 6 ]. Fasciolosis in sheep has also been associated with a variety of conditions including black disease (infection by Clostridium novyi ), parasitic gastroenteritis and metabolic diseases, especially around lambing time, such as hypocalcaemia and pregnancy toxaemia [ 7 ]. It is also a predisposing risk factor for mastitis [ 8 ], and inflammatory mediators from liver damage may affect early pregnancy [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

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Fasciolosis—An Increasing Challenge in the Sheep Industry

Stuen

Ersdal

2022

Animals

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The liver fluke Fasciola hepatica may cause severe infection in several mammalian species, including sheep and humans. Fasciolosis is a parasitic disease occurring worldwide in temperate climates and involves intermediate lymnaeid snails as vectors, in Europe the pond snail Galba truncatula in particular. In the sheep industry, the disease is a serious welfare and health problem. Fasciolosis is usually classified as acute, subacute or chronic according to the number and stage of flukes present in the liver, but with a considerable overlap. Acute disease, associated with a large number of migrating larvae, often results in sudden death due to acute and massive hemorrhage, while chronic fasciolosis is characterized by anemia, hypoalbuminaemia and weight loss. The management of fasciolosis is an increasing challenge in the sheep industry. Early diagnostic tests are limited. Protective immunity against liver flukes in sheep is low or lacking, and vaccines are not yet available. Treatment and control possibilities are challenging, and resistance to flukicide drugs is increasing. In addition, climate change with warmer and more humid weather will have a substantial effect on the establishment of both flukes and snails and will most likely increase the future distribution of F. hepatica.

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Section: Life Cyclementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fasciolosis—An Increasing Challenge in the Sheep Industry

Stuen

Ersdal

2022

Animals

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“…Kerugian ekonomi yang utama didasarkan akibat terbuangnya hati baik sebagian maupun seluruhnya serta biaya pembelian obat-obatan dan tenaga ahli seperti dokter hewan (Mitchell, 2007;Kusumamihardja, 1992).…”

Section: Pendahuluanunclassified

TINGKAT KERENTANAN Fasciola gigantica PADA SAPI DAN KERBAU DI KECAMATAN LHOONG KABUPATEN ACEH BESAR

Hambal¹,

Sayuti²,

Dermawan³

2013

J.Med.Vet.

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ABSTRAKPenelitian ini bertujuan mendapatkan informasi tentang perbedaan tingkat kerentanan sapi dan kerbau terhadap Fasciola gigantica di Kecamatan Lhoong, Kebupaten Aceh Besar. Sampel diperoleh dari lima desa yang terdapat di Kecamatan Lhoong, Kabupaten Aceh Besar. Sampel terdiri atas 150 ekor sampel feses kerbau dan 150 sampel feses sapi segar, masing-masing terdiri atas 75 ekor sampel feses kerbau jantan, 75 ekor sampel feses kerbau betina,75 ekor sampel feses sapi jantan, 75 ekor sampel feses sapi betina. Identifikasi dan perhitungan telur Fasciola gigantica menggunakan metode sedimentasi modifikasi Borray. Hasil penelitian dianalisis secara deskriptif. Dari hasil penelitian terlihat perbedaan tingkat kerentanan sapi dan kerbau terhadap Fasciola gigantica di Kecamatan Lhoong Kabupaten Aceh Besar dengan total prevalensi pada kerbau jantan; kerbau betina; sapi jantan; dan sapi betina masing-masing adalah 93,3; 90,6; 92,0; dan 89,3%. Rata-rata intensitas telur pada kerbau jantan; kerbau betina; sapi jantan; dan sapi betina masing-masing adalah 26,16; 29,11; 20,96; dan 10,29. Rata-rata intensitas telur pada kerbau dan sapi masing-masing 25,40 dan 14,24. Prevalensi pada kerbau umur 0-6, 7-12, dan >12 bulan masing-masing adalah 80, 96, dan 100%. Prevalensi pada sapi umur 0-6, 7-12, dan >12 bulan masing-masing adalah 78, 100, 94%. Intensitas telur pada kerbau umur 0-6; 7-12; dan>12 bulan masing-masing adalah 7,79; 19,49; dan 51,27. Intensitas telur pada sapi umur 0-6; 7-12; dan>12 bulan masing-masing adalah7

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“…infection mainly by F. gigantica causing weight loss, lame growth and low endurance and damage the liver and bile as well (Mitchell, 2007). The prevalence of liver flukes by F. gigantica in Indonesia reached 90% (Abidin, 2002).…”

Section: Introductionmentioning

confidence: 99%

Identification of Excretory Secretory (ES) Liquid Antigen Protein Fasciola gigantica with Polyethilen Glycol (PEG) Separation

Junaidi

Malawati

Sriasih

2017

Indones. J. Biotechnol.

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Fasciola gigantica diagnosis usually performed by detection of worm eggs presence in the feces, but this conventional method has many disadvantages. Early diagnosis (early detection) cannot be performed in conventional methods because the worms in the host's body began to lay eggs at the age of 8-12 weeks of patency. The current detection method that is based on antibodyantigen reactions using excreted/secreted (ES) liquid by adult F. gigantica, is believed to be used for the early detection of fasciolosis. This study aimed to characterize the antigenic components of F. gigantica extretory/secretory products that could be used as a vaccine candidate development for early fasciolosis diagnostics. ES products were separated by PEG4000 at various concentrations (8%, 16%, 24%), then precipitates (pellets) obtained were dialyzed and characterized using SDSPAGE and Western blotting. Results from SDS PAGE showed that there were 18 proteins bands with 7-70 kDa molecular weights. Western blotting on pellets derived from PEG separation at various concentrations affirmed that the proteins of 50, 25 and 20 kDa were antigenic at 8% PEG concentration, the 25 kDa and 50 kDa were antigenic at 16% PEG concentrations and the 25 kDa was antigenic at 25% PEG concentration.

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Liver Fluke

Cited by 7 publications

References 4 publications

Fasciolosis—An Increasing Challenge in the Sheep Industry

Fasciolosis—An Increasing Challenge in the Sheep Industry

TINGKAT KERENTANAN Fasciola gigantica PADA SAPI DAN KERBAU DI KECAMATAN LHOONG KABUPATEN ACEH BESAR

Identification of Excretory Secretory (ES) Liquid Antigen Protein Fasciola gigantica with Polyethilen Glycol (PEG) Separation

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