Liver function and plasma antioxidant status in intensive care unit patients requiring total parenteral nutrition: comparison of 2 fat emulsions

Antébi, H.; Mansoor, O.; Ferrier, C.; Tetegan, M.; Morvan, C.; Rangaraj, J; Lg, Alcindor

doi:10.1177/0148607104028003142

Cited by 121 publications

(113 citation statements)

References 46 publications

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“…Recently, supplementation with fish oil is supposed to improve standard clinical therapy for chronic hyper-inflammatory diseases such as Crohn' disease [1,5] , rheumatoid arthritis [6] , cancer cachexia [7,8] , and as an adjunct therapeutic measure for trauma, injure, and sepsis [2,[9][10][11][12] . Although several studies have demonstrated the beneficial effects of omega-3 fatty acid supplementation on patient outcome or immune competence, randomized controlled clinical trials focusing on the use of parenteral fish oil are scarce [13][14][15][16][17] . The aim of this study was to assess whether parenteral supplementation of omega-3 fatty acid postoperatively improves the inflammatory and immunological function of colorectal cancer patients and their clinical outcomes.…”

Section: Introductionmentioning

confidence: 99%

Impact of postoperative omega-3 fatty acid-supplemented parenteral nutrition on clinical outcomes and immunomodulations in colorectal cancer patients

Liang¹,

Wang²,

Ye³

et al. 2008

WJG

120

143

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AIM:To investigate the effect of omega-3 fatty acid parenteral supplementation postoperatively on clinical outcomes and immunomodulation in colorectal cancer patients. METHODS:Forty-two patients undergoing radical colorectal cancer resection with an indication for total parenteral nutrition postoperatively were enrolled in this prospective, double-blind, randomized, controlled study. Patients received total parenteral nutrition supplemented with either soybean oil (LCT; Intralipid CONCLUSION:Postoperative supplementation of omega-3 fatty acids may have a favorable effect on the outcomes in colorectal cancer patients undergoing radical resection by lowering the magnitude of inflammatory responses and modulating the immune response.

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Section: Introductionmentioning

confidence: 99%

Impact of postoperative omega-3 fatty acid-supplemented parenteral nutrition on clinical outcomes and immunomodulations in colorectal cancer patients

Liang¹,

Wang²,

Ye³

et al. 2008

WJG

120

143

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“…This emulsion is designed to increase the amount of n-3 fatty acids, thereby reducing the ratio of n-6 to n-3 fatty acids (in accordance with current recommended levels). 43 SMOFlipid 20% is well tolerated in infants without changing lipid peroxidation parameters, 31,44 and beneficial effects on liver function and serum triglyceride concentrations have been described. 31 …”

Section: Risks and Benefits Of Parenteral Nutritionmentioning

confidence: 99%

Nutritional Evaluation and Optimisation in Neonates (NEON) trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition: a randomised double-blind controlled trial

et al. 2016

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Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising.The WestminsterResearch online digital archive at the University of Westminster aims to make the research output of the University available to a wider audience. Copyright and Moral Rights remain with the authors and/or copyright owners.Whilst further distribution of specific materials from within this archive is forbidden, you may freely distribute the URL of WestminsterResearch: ((http://westminsterresearch.wmin.ac.uk/).In case of abuse or copyright appearing without permission e-mail repository@westminster.ac.uk This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE) (www.publicationethics.org/). EFFICACY AND MECHANISM EVALUATION Efficacy and Mechanism EvaluationEditorial contact: nihredit@southampton.ac.ukThe full EME archive is freely available to view online at www.journalslibrary.nihr.ac.uk/eme. Print-on-demand copies can be purchased from the report pages of the NIHR Journals Library website: www.journalslibrary.nihr.ac.uk Criteria for inclusion in the Efficacy and Mechanism Evaluation journalReports are published in Efficacy and Mechanism Evaluation (EME) if (1) they have resulted from work for the EME programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors. EME programmeThe Efficacy and Mechanism Evaluation (EME) programme was set up in 2008 as part of the National Institute for Health Research (NIHR) and the Medical Research Council (MRC) coordinated strategy for clinical trials. The EME programme is broadly aimed at supporting 'science driven' studies with an expectation of substantial health gain and aims to support excellent clinical science with an ultimate view to improving health or patient care.Its remit includes evaluations of new treatments, including therapeutics (small molecule and biologic), psychological interventions, public health, diagnostics and medical devices. Treatments or interventions intended to prevent disease are also included.The EME programme supports laboratory based or similar studies that are embedded within the main study if relevant to the remit of the EME programme. Studies that use validated surrogate markers as indicators of health outcome are also considered.For more information about the EME programme please visit the website: http://www.nets.nihr.ac.uk/programmes/eme This reportThe research reported in this issue of the journal was funded by the EME programme as project number 08/99/04. The contractual start date was in February 2010. The final report began editorial review in January 2015 and was accepted for publication in October 2015. The authors have been wholly responsible for all data collection, analysis and interpretation, and for writing up their work. The EME edit...

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“…The use of early PN is quite common nowadays and its demand is rapidly increasing for the pediatric population especially in preterm neonates [17]. In this systematic review, the benefits and harmful effects of lipid emulsion has been described on the account of clinical outcomes, by the introduction of lipid in early and late life days.…”

Section: Discussionmentioning

confidence: 99%

Effects of Early and Late Parenteral Nutrition on Clinical Outcomes in Very Low Birth Weight Preterm Infants: A Systematic Review and Meta-analysis

Kotiya¹,

Zhu²

2015

J Neonatal Biol

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Liver function and plasma antioxidant status in intensive care unit patients requiring total parenteral nutrition: comparison of 2 fat emulsions

Cited by 121 publications

References 46 publications

Impact of postoperative omega-3 fatty acid-supplemented parenteral nutrition on clinical outcomes and immunomodulations in colorectal cancer patients

Impact of postoperative omega-3 fatty acid-supplemented parenteral nutrition on clinical outcomes and immunomodulations in colorectal cancer patients

Nutritional Evaluation and Optimisation in Neonates (NEON) trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition: a randomised double-blind controlled trial

Effects of Early and Late Parenteral Nutrition on Clinical Outcomes in Very Low Birth Weight Preterm Infants: A Systematic Review and Meta-analysis

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