Liver glycogen alterations in anæsthesia and surgery

Effects of Spinal Anaesthesia and Surgery on Carbohydrate and Fat Metabolism in Man

“…This is in contrast to the marked hyperglycaemic influence of surgical stress under general anaesthesia (Bunker, 1963). Annamundiodo, Keating and Patrick (1958) observed that during spinal anaeschesia with hyperbaric cinchocaine the blood glucose level or muscle glycogen content did not significantly alter. Kleinerman, Sancetta and Hackel (1958) reported similar findings during spinal anaesthesia with hyperbaric procaine.…”

The Anaesthetic Ethers

“…The most striking metabolic effect of diethyl ether is the production of hyperglycaemia. This is due to an increased rate of formation of glucose from hepatic glycogen (Annamunthodo et al, 1958). Hyperglycaemia does not occur in hepatectomized animals (Bollman et aL, 1925), and is less pronounced in man with liver disease (Cantarrow and Gehret, 1931).…”

The Blood Sugar Response to Anaesthesia and Surgery in Southern Indians

“…Studies of blood sugar values during anaesthesia and surgery were conducted because several authors have suggested that the response of hyperglycaemia as a result of catecholamine release is an effective, if crude, indicator of the stress response (Keating, 1958;Annamunthodo, Keating and Patrick, 1958). There are differences between people from the various parts of India, but the patients studied came from the immediate locality of Vellore and can be regarded as a typical sample of South Indians.…”