The Blood Sugar Response to Anaesthesia and Surgery in Southern Indians

Abstract

SUMMARYDuring the course of anaesthesia and surgery in South India, it was noticed that Indian and European patients responded differently. In an attempt to evaluate these differences, blood sugar values were used as a guide to the sympathetic nervous response. Under general anaesthesia values rose and stayed higher in Indian patients than in Europeans in India or England. General anaesthesia by itself provoked no elevation until the commencement of surgical trauma. Under subarachnoid or epidural analgesia, no major change in blood sugar occurred during surgery. During the study involving 141 patients, three collapsed unexpectedly and resuscitative measures invalidated the blood sugar results. Although nutrition might play some part, the differences are considered to be racial and not climatic.

Clinical Studies of Induction Agents Xxiv: The Influence of Anaesthesia With Thiopentone and Propanidid on the Blood Sugar Level

“…Furthermore, the latter two groups have also shown that glucose metabolism is not impaired by thiopentone anaesthesia, and discrepancies between workers may be attributed to species variation and the use of very high dosage in animals. Race of patient and site of operation also influence the response (Keating, 1958;Keating, Patrick and Annamunthodo, 1959;Cullingford, 1966) but whether the rise is harmful, as these workers have suggested, remains an open question. It would seem worth investigating whether the hyperglycaemic reaction is related to the amount of trauma, and whether it can be prevented, if only to understand more about its mechanism.…”

Comparing hemodynamic and glycemic response to local anesthesia with epinephrine and without epinephrine in patients undergoing tooth extractions

“…[6910] Such concentrations may be obtained shortly after the injection of clinical doses of adrenaline containing LA. [611]…”

“…[123456789101112131415161718192021222324252627] The present study was done to comparatively evaluate the effects of 2% lignocaine and 2% lignocaine with 1:200,000 epinephrine on blood glucose level and hemodynamics in patients undergoing multiple tooth extractions.…”

Effects of Hydroxyethyl Starches on Blood Sugar Levels Under Subarachnoid Block During Surgery

“…Among the above mentioned responses, hyperglycemia can be detrimental to the well-being of the patient. 9,10 Hyperglycemia can potentiate brain, spinal cord and renal damage by ischemia.…”