We are glad to note that both the authors and we are in agreement that liver transplantation (LT) ought not to be perceived as the first option in treating tyrosinemia type 1 (TT-1) [1]. Our first response came from the belief that we differ in aspiration-the authors emphasized on just how well LT works, but we felt that such emphasis is slightly misplaced and what needs to take center stage is the apparent need to start newborn screening and make nitisinone accessible [2]. We thank the authors for clarifying that they share our aspiration, and feel compelled to clarify that our disagreement is now linguistic.