LncRNA SOCS2-AS1 promotes the progression of papillary thyroid cancer by destabilizing p53 protein

Zhang, Xiaojian; Zhang, Xiaozhou; Yang, Guang; Wan, Long; Yin, Feng-yan; Li, Hongqiang; Yin, Dengke

doi:10.1016/j.bbrc.2023.05.080

Cited by 3 publications

(2 citation statements)

References 24 publications

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“… 33 Zhang et al demonstrated that the lncRNA SOCS2-AS1 was highly expressed in papillary thyroid cancer and that patients with a high level of SOCS2-AS1 had a poor survival rate, with enhanced PTC cell proliferation through the destabilization of p53 protein. 34 Misawa et al demonstrated that SOCS2-AS1 contributed to the development of castration-resistant prostate cancer by inhibiting apoptosis. 35 Recently, Zhong et al reported that the expression of SOCS2-AS1 was low in NANOG+ HCC stem cells and that patients with a high level of SOCS2-AS1 had a poor prognosis through the regulation of miR-454-3p/CPEB1.…”

Section: Discussionmentioning

confidence: 99%

The Potential of the lncRNAs ADAMTSL4-AS1, AC067931 and SOCS2-AS1 in Peripheral Blood Mononuclear Cells as Novel Diagnostic Biomarkers for Hepatitis B Virus-Associated Hepatocellular Carcinoma

Guan,

Zhang,

Miao

et al. 2024

JHC

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Section: Discussionmentioning

confidence: 99%

The Potential of the lncRNAs ADAMTSL4-AS1, AC067931 and SOCS2-AS1 in Peripheral Blood Mononuclear Cells as Novel Diagnostic Biomarkers for Hepatitis B Virus-Associated Hepatocellular Carcinoma

Guan,

Zhang,

Miao

et al. 2024

JHC

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“…SOCS2‐AS1 binds to P53 directly and facilitates its degradation, further stimulating FAO‐mediated cell proliferation. [ 145 ]…”

Section: Lncrnas‐circrnas Regulate the Rewiring Of Lipid Metabolism I...mentioning

confidence: 99%

LncRNAs‐circRNAs as Rising Epigenetic Binary Superstars in Regulating Lipid Metabolic Reprogramming of Cancers

Liu,

Jiao,

Zhao

et al. 2023

Advanced Science

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As one of novel hallmarks of cancer, lipid metabolic reprogramming has recently been becoming fascinating and widely studied. Lipid metabolic reprogramming in cancer is shown to support carcinogenesis, progression, distal metastasis, and chemotherapy resistance by generating ATP, biosynthesizing macromolecules, and maintaining appropriate redox status. Notably, increasing evidence confirms that lipid metabolic reprogramming is under the control of dysregulated non‐coding RNAs in cancer, especially lncRNAs and circRNAs. This review highlights the present research findings on the aberrantly expressed lncRNAs and circRNAs involved in the lipid metabolic reprogramming of cancer. Emphasis is placed on their regulatory targets in lipid metabolic reprogramming and associated mechanisms, including the clinical relevance in cancer through lipid metabolism modulation. Such insights will be pivotal in identifying new theranostic targets and treatment strategies for cancer patients afflicted with lipid metabolic reprogramming.

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Progress in long non-coding RNAs as prognostic factors of papillary thyroid carcinoma

Zhu,

Song,

Zhang

et al. 2024

Pathology - Research and Practice

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LncRNA SOCS2-AS1 promotes the progression of papillary thyroid cancer by destabilizing p53 protein

Cited by 3 publications

References 24 publications

The Potential of the lncRNAs ADAMTSL4-AS1, AC067931 and SOCS2-AS1 in Peripheral Blood Mononuclear Cells as Novel Diagnostic Biomarkers for Hepatitis B Virus-Associated Hepatocellular Carcinoma

The Potential of the lncRNAs ADAMTSL4-AS1, AC067931 and SOCS2-AS1 in Peripheral Blood Mononuclear Cells as Novel Diagnostic Biomarkers for Hepatitis B Virus-Associated Hepatocellular Carcinoma

LncRNAs‐circRNAs as Rising Epigenetic Binary Superstars in Regulating Lipid Metabolic Reprogramming of Cancers

Progress in long non-coding RNAs as prognostic factors of papillary thyroid carcinoma

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