Local infusion analgesia using intra-articular double lumen catheter after total knee arthroplasty: a double blinded randomized control study

Ikeuchi, Masahiko; Kamimoto, Yuko; Izumi, Masashi; Sugimura, Natsuki; Takemura, Mizue; Fukunaga, K.; Yokoyama, Masataka; Tani, Tohru

doi:10.1007/s00167-012-2004-8

Cited by 24 publications

(25 citation statements)

References 28 publications

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“…The characteristics of the 11 included trials are summarized in ►Table 3. 6,10,[20][21][22][23][24][25][26][27][28] A total of 453 TKAs in 374 patients were included in this review.…”

Section: Included Studiesmentioning

confidence: 99%

“…25,28 Five articles were eligible for meta-analysis on the effect of CLIA versus placebo, involving 227 TKAs. 10,23,24,27,28 Two studies were eligible for the effect of CLIA versus SLIA (84 TKAs). 25,28 Others were not suitable for the meta-analysis due to lack of reporting relevant data (►Table 4).…”

Section: Included Studiesmentioning

confidence: 99%

“…Heterogeneity between the studies was 16%. 10,23,24,27,28 After the second and third postoperative day, the decrease in VAS scores at rest was no longer significant (►Figs. 3 and 4).…”

Section: Pain Scores At Restmentioning

confidence: 99%

“…3 and 4). 10,23,24,27,28 Pain Score during Activity During activity (mobilization or walking) VAS scores were in favor of CLIA compared with placebo after 24 hours (►Figs. 5 and 6).…”

Section: Pain Scores At Restmentioning

confidence: 99%

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Continuous Local Infiltration Analgesia after TKA: A Meta-Analysis

Keijsers

Bekerom²,

Delft

et al. 2015

J Knee Surg

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The analgesic effect of local infiltration analgesia (LIA) after total knee arthroplasty (TKA) has been reported to be less than 24 hours. The concept of continuous LIA (CLIA) has been developed to achieve prolonged analgesia by bolus injections or by pump infusion of analgesics. The purpose of this meta-analysis is to assess the effect of CLIA versus single-shot injection LIA (SLIA) and placebo on pain after TKA.A systematic search was performed in most relevant databases to identify all randomized controlled trials (RCTs) comparing intra-articular CLIA with SLIA or placebo for TKA. Primary outcome measures were visual analogue scale (VAS)-scores after 24, 48, and 72 hours at rest and during activity. Data were extracted for meta-analysis and pooled using Cochrane software. The results of comparable studies were pooled using the fixed effects model or random effects model.A total of 11 RCTs were included. Five articles were eligible for meta-analysis comparing CLIA versus placebo, involving 227 TKAs. VAS scores at rest 24 hours after surgery were in favor of CLIA with a decrease of pain scores of 46%. On the second and third postoperative day, the decrease in VAS scores was no longer significant. During activity VAS scores were also in favor of CLIA after 24 and 48 hours.Two studies were eligible for meta-analysis comparing CLIA versus SLIA. VAS scores at rest, 48 hours after surgery, were in favor of CLIA. CLIA can possibly provide a reduced pain perception for 24 hours postoperative at rest after performing a TKA. This effect may persist until 48 hours postoperative during activity. Due to the high level of heterogeneity no firm further conclusions can be drawn.

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“…The characteristics of the 11 included trials are summarized in ►Table 3. 6,10,[20][21][22][23][24][25][26][27][28] A total of 453 TKAs in 374 patients were included in this review.…”

Section: Included Studiesmentioning

confidence: 99%

Section: Included Studiesmentioning

confidence: 99%

“…Heterogeneity between the studies was 16%. 10,23,24,27,28 After the second and third postoperative day, the decrease in VAS scores at rest was no longer significant (►Figs. 3 and 4).…”

Section: Pain Scores At Restmentioning

confidence: 99%

“…3 and 4). 10,23,24,27,28 Pain Score during Activity During activity (mobilization or walking) VAS scores were in favor of CLIA compared with placebo after 24 hours (►Figs. 5 and 6).…”

Section: Pain Scores At Restmentioning

confidence: 99%

See 2 more Smart Citations

Continuous Local Infiltration Analgesia after TKA: A Meta-Analysis

Keijsers

Bekerom²,

Delft

et al. 2015

J Knee Surg

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“…[1][2][3] Intra-articular analgesia is a viable alternative. [4][5][6][7][8][9] This study compared the efficacy of epidural versus intraarticular infusion analgesia following TKR.…”

Section: Introductionmentioning

confidence: 99%

Epidural versus Intra-Articular Infusion Analgesia following Total Knee Replacement

Kasture¹,

Saraf

2015

J Orthop Surg (Hong Kong)

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Purpose.To compare the efficacy of epidural versus intra-articular infusion analgesia following total knee replacement (TKR). Methods. 25 men and 50 women aged 55 to 75 (mean, 67) years who underwent primary TKR by a single surgeon were randomised and consented to receive either epidural (n=35) or intra-articular (n=40) infusion analgesia for 48 hours at 5 ml/ hr. All patients also received intravenous aqueous diclofenac 50 mg twice a day. Patients were assessed 6 hourly for visual analogue score (VAS) for pain to determine the analgesic effect. Complications such as paraesthesia in the lower limbs, hypotension, urinary retention, and abdominal distension were recorded, as was the rehabilitation progress with respect to the time to stand, climb stairs, use of commode chair, and discharge. Results. The epidural and intra-articular infusion groups were comparable with respect to age, sex, weight, and operating time, as was the analgesic Epidural versus intra-articular infusion analgesia following total knee replacement

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Perioperative Pain Management

Tsukada

2024

Advances in Total Knee Arthroplasty

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Local infusion analgesia using intra-articular double lumen catheter after total knee arthroplasty: a double blinded randomized control study

Abstract: Although larger studies are needed to examine its safety, the local infusion analgesia alone provided clinically significant analgesic effects and rapid recovery in total knee arthroplasty.

Cited by 24 publications

References 28 publications

Continuous Local Infiltration Analgesia after TKA: A Meta-Analysis

Continuous Local Infiltration Analgesia after TKA: A Meta-Analysis

Epidural versus Intra-Articular Infusion Analgesia following Total Knee Replacement

Perioperative Pain Management

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