“…In comparing the effectiveness of different therapeutic agents commonly used for TPI, it appears that relief of pain is mainly due to the needle effect rather than to which specific injected medications are used (31)(32)(33)(34)(35)(36)(37)(38). In a doubleblinded study of 107 patients who had pain in the lateral aspect of the face and TPs in the masticatory muscles, local injection therapy using one of three solutions (1 mL 0.25% bupivacaine, 1% lidocaine, or 0.9% saline) yielded no significant differences between the agents in pain relief achieved or in the overall assessment of the therapeutic effect (31). Similarly, in a prospective, randomized evaluation of TPI therapy for lower back pain, there was no significant difference in outcome between injections of lidocaine, lidocaine combined with a steroid, or dry needling at 2 weeks after treatment (37).…”