Local Membrane Current in the Outer Segments of Squid Photoreceptors

Hagins, W. A.; Zonana, H. V.; Adams, Ralph G.

doi:10.1038/194844a0

Cited by 119 publications

(24 citation statements)

References 11 publications

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“…retinal surface was a slow negative response with respect to the back of the eye, and that the surface response changed its polarity from negative to positive as a microelectrode was advanced deeper into the retina. In agreement with the previous studies in the cephalopod retina (Hagins et al 1962;Tasaki et al 1963) the present finding obtained with a penetrating microelectrode could be explained by assuming that the distal segments of the receptor cells would be depolarized by light. Such depolarization of the receptor cell is expected to act as a generator potential for the optic nerve fiber as demonstrated in the isolated retina of the land snail (Gillary and Wolbarsht 1967).…”

Section: Discussionsupporting

confidence: 82%

“…However, that the response reversed in polarity from negative to positive during the retinal penetration indicates the existence of an electric dipole layer in the retina. The structural basis for this double layer could well be an array of the receptor cells of which distal portion is depolarized by light as in the case of the other mulluscan retinas (Hagins et al 1962;Tasaki et al 1963; Gillary and Wolbarsht 1967).…”

Section: Resultsmentioning

confidence: 99%

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Fast and Slow Components in the Electroretinogram of the Gastropod

Karita

Ito

Tasaki

1973

Tohoku J. Exp. Med.

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Section: Discussionsupporting

confidence: 82%

Section: Resultsmentioning

confidence: 99%

Fast and Slow Components in the Electroretinogram of the Gastropod

Karita

Ito

Tasaki

1973

Tohoku J. Exp. Med.

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“…Because of such structural simplicity and the superficial arrangement of the rhabdomes, the cephalopod retina has been one of the most favorable materials used not only for studying the comparative physiology of the retina but also for the investigation of the photoreceptive mechanism in primary sensory cells (4,7,17,(23)(24)(25).…”

Section: Introductionmentioning

confidence: 99%

Fine Structure of the Octopus Retina

Yamamoto

Tasaki

Sugawara

et al. 1965

The Journal of Cell Biology

120

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The fine structure of the visual and the supporting cells and of the blood capillaries in the octopus retina is described. Lamellatcd structures contained in the proximal segment of the visual cell consist of compact arrays of dense membranes each of which is quintuplelayered and divides at its margins into two thinner sheets or membranes which are connected directly with the agranular or granular cndoplasmic reticulum. Proximal to the deeper extremitics of the rhabdomcres, the lateral plasma membranes of two adjoining visual cells contact each other forming a quintuple-layered compound membrane, which results in occlusion of the intercellular space. The central layer of the compound membrane is of high density, so that thc membrane, as a whole, appears to be a single thick layer at low magnifications. The supporting cells are connccted with the neighboring visual cells by two typcs of junctions. Long slender processes extend from the supporting cells to the surface of the retina through narrow spaccs among the distal segments of the visual cells. The capillary cndothclial cclls are charactcrized by luminal surfaces irregularly contoured and by lateral surfaccs clahorately interdigitatcd. The functional significancc of the close contact between adjoining visual cclls is discussed.

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“…However, since light scattering could seriously compromise the validity of the above experiment, we tried to obtain more evidence of stimulus localization. Our control experiment was similar to previous experiments in squid (Hagins et al 1962), Limulus (Fein and Charlton 1975), frog (Jagger 1979), toad (McNaughton et al 1980), drone bee (Bader et al 1982), and fly (Minke and Payne 1990). After measuring average responses to test flashes at two sites separated by 120 gm, one of these sites (the central site, closer to the recording electrode, as in Fig.…”

Section: Localized Adaptationmentioning

confidence: 77%

Sublinear summation of responses in locust photoreceptors

Pece

French

1992

J Comp Physiol A

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Summary. The response of a locust, Locusta miyratoria,photoreceptor to a simultaneous pair of dim flashes is smaller than the sum of the responses to the individual component flashes, even when the photon absorption sites are separated by a distance of 120 ~tm, which should prevent them from interacting biochemically. A similar depression is observed when a flash is paired with a depolarizing current instead of a second flash, irrespective of whether the flash response precedes or follows the current response. These results indicate that the sublinear summation is caused by the activation of a voltageactivated shunting conductance. This conductance is not blocked by low intracellular concentrations of tetraethylammonium chloride, and is therefore different from the conductance which causes the decrease of the receptor's step response from transient to steady-state.

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Local Membrane Current in the Outer Segments of Squid Photoreceptors

Cited by 119 publications

References 11 publications

Fast and Slow Components in the Electroretinogram of the Gastropod

Fast and Slow Components in the Electroretinogram of the Gastropod

Fine Structure of the Octopus Retina

Sublinear summation of responses in locust photoreceptors

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