Local Recurrence of Disease after Unplanned Excisions of High-grade Soft Tissue Sarcomas

Abstract

Level II, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.

Short-term follow-up MRI after unplanned resection of malignant soft-tissue tumours; quantitative measurements on dynamic contrast enhanced and diffusion-weighted MR images

“…1 However, sometimes, unplanned resections are carried out because surgeons fail to consider sarcoma. Unplanned resection is defined as resection of presumed benign masses without appropriate pre-operative imaging, biopsy or attention to surgical margins.…”

Clinical and Treatment Outcomes of Planned and Unplanned Excisions of Soft Tissue Sarcomas

“…Several previous studies emphasize the problems of an unplanned excision showing the higher incidence of local recurrence even after additional surgery [12] or residual tumor in reexcision specimens [2,3,11,17]. Several studies have evaluated the disease-specific survival, metastasis-free survival, and local recurrence-free survival of the patients with unplanned excisions for musculoskeletal tumors in comparison to the patients with planned excisions [8,12,16].…”

“…Several studies have evaluated the disease-specific survival, metastasis-free survival, and local recurrence-free survival of the patients with unplanned excisions for musculoskeletal tumors in comparison to the patients with planned excisions [8,12,16]. One of these studies suggested patients with unplanned excision followed by additional wide resection had as good or better disease-specific and metastasis-free survival compared with those with planned excision [8].…”

What Are Risk Factors for Local Recurrence of Deep High-grade Soft-tissue Sarcomas?

“…Whether patients undergoing unplanned excision of their primary sarcoma have a higher risk of local recurrence is controversial [2,4,10,13]. Several studies suggest unplanned excisions of soft-tissue sarcomas result in increased rates of local recurrence, mainly because of residual tumor [4,10].…”

“…Several studies suggest unplanned excisions of soft-tissue sarcomas result in increased rates of local recurrence, mainly because of residual tumor [4,10]. While patients with unplanned excisions tend to have superficial tumors, other reports show no adverse impact of unplanned excision on local recurrence [2,13].…”