Local staging of prostate cancer by endorectal MRI using fast spin‐echo sequences: prospective correlation with pathological findings after radical prostatectomy

Cornud, F.; Belin, X.; Flam, T.; Chrétien, Yves; Deslignières, S; Paraf, F; Casanova, J. M.; Thiounn, Nicolas; Hélénon, O.; Debré, B; Dufour, B; Moreau, Jean-François

doi:10.1046/j.1464-410x.1996.01313.x

Cited by 55 publications

(24 citation statements)

References 2 publications

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“…Current clinical methods used in the staging of prostate cancer (digital rectal examination, PSA, transrectal ultrasound, bone scanning) have limited value to predict the extent of disease [2]. 40-50% of patients operated on for clinically localized tumors show extraprostatic spread on pathologic examination [3]. Magnetic resonance imaging (MRI) can be used in the staging of prostate cancer and is a promising imaging modality for evaluating the pelvis because of its high contrast sensitivity and its direct multiplanar imaging capability [4].…”

Section: Introductionmentioning

confidence: 99%

Is Magnetic Resonance Imaging Necessary in the Staging of Prostate Cancer?

Tüzel¹,

Sevinç²,

Obuz³

et al. 1998

Urol Int

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Objective: To evaluate the necessity of using magnetic resonance imaging (MRI) in the staging of patients with clinically localized prostate cancer. Methods: Sixty-one patients with prostate cancer were evaluated with MRI for preoperative staging with a conventional body-coil (Siemens Magnetom, 1.0 Tesla superconducting system). Twenty-nine patients underwent radical prostatectomy for presumed clinically localized disease. Of those, 17 were staged both with MRI and computerized tomography (CT). The remaining patients were staged with CT alone. MRI and CT findings, and the final pathologic staging of patients are reviewed. Results: On pathological examination of the surgical specimens, the tumor was found to extend beyond the prostate in 7 patients (41%). Among the 17 patients who were operated, extraprostatic extension (EPE) was detected accurately in 3 patients with MRI (sensitivity 20%, specificity 92%, accuracy 70.5%). No metastatic lymph nodes were detected on the basis of MRI (sensitivity 0%, specificity 93%, accuracy 88.2%). In 1 patient EPE was correctly identified by CT (sensitivity 14%, specificity 100%, accuracy 64.7%). Conclusion: Neither MRI with conventional body-coild nor CT are sufficient to indicate local extension of disease in clinically localized prostate cancer.

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Section: Introductionmentioning

confidence: 99%

Is Magnetic Resonance Imaging Necessary in the Staging of Prostate Cancer?

Tüzel¹,

Sevinç²,

Obuz³

et al. 1998

Urol Int

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show abstract

“…22 Other examples illustrating the controversy include a study from 1996, which showed a reduction in understaging from 42 to 22% and a specificity for extracapsular invasion of 96% using the ERC. 23 Another group in the same year suggested that staging with ERC MRI overstaged 21% of the study group, denying them a potentially curative procedure and advised against routine use of MRI in staging. 9 While the controversy continues, accuracy for demonstrating seminal vesicle invasion, particularly with combined ER-PPA coil, appears to be consistently high, up to 94%.…”

Section: Staging Accuracy and Indicationsmentioning

confidence: 99%

Magnetic resonance imaging in prostate cancer

Heenan

2004

Prostate Cancer Prostatic Dis

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With the recently published National Institute of Clinical Excellence guidelines, it is now generally accepted that magnetic resonance imaging (MRI) is the imaging method of choice for staging prostate cancer in patients for whom radical treatment is being considered. MRI offers the single most accurate assessment of local disease and regional metastatic spread. As well as detecting extraprostatic extension, this technique can locate the site of intraprostatic disease, which may prove useful in planning disease-targeting therapies currently being developed. However, numerous studies have reported widely varying accuracies indicating that MRI is not the perfect imaging modality; microscopic and early macroscopic invasion cannot be reliably shown using current technology. The role of MRI including advantages, limitations and future developments will be discussed.

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“…Este método tem critérios de imagem objetivos e definidos para a caracterização de invasão extraprotática, ou seja, tem boa especificidade na predição de extravasamento tumoral extracapsular e invasão de vesículas seminais (48,49). Considera-se como na TC, linfonodos suspeitos de positividade aqueles > 1 cm em seu maior eixo, apesar de alguns estudos demonstrarem ineficácia da análise do tamanho, pois existem linfonodos positivos menores que 1 cm e outros d este tamanho ou maior apenas com reação inflamatória.…”

Section: Imagem E Estadiamentounclassified

O estudo do impacto do rastreamento no estadiamento clínico dos portadores de câncer de próstata

Faria¹

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Local staging of prostate cancer by endorectal MRI using fast spin‐echo sequences: prospective correlation with pathological findings after radical prostatectomy

Cited by 55 publications

References 2 publications

Is Magnetic Resonance Imaging Necessary in the Staging of Prostate Cancer?

Is Magnetic Resonance Imaging Necessary in the Staging of Prostate Cancer?

Magnetic resonance imaging in prostate cancer

O estudo do impacto do rastreamento no estadiamento clínico dos portadores de câncer de próstata

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