Localized double spin echo proton spectroscopy part I: Basic concepts

Jung, Wulf‐Ingo

doi:10.1002/(sici)1099-0534(1996)8:1<1::aid-cmr1>3.0.co;2-2

Cited by 8 publications

(2 citation statements)

References 12 publications

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“…The PRESS localization method [30][31][32][33] is a so-called double spin-echo method, in which slice-selective excitation is combined with two slice-selective refocusing pulses ( Figure 6.13). When the first 180 • pulse is executed after a time t 1 following the excitation pulse, a spin-echo is formed at time 2t 1 .…”

Section: Point Resolved Spectroscopy (Press)mentioning

confidence: 99%

Single Volume Localization and Water Suppression

Graaf

Robin²

2007

In Vivo NMR Spectroscopy

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Section: Point Resolved Spectroscopy (Press)mentioning

confidence: 99%

Single Volume Localization and Water Suppression

Graaf

Robin²

2007

In Vivo NMR Spectroscopy

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“…Although standard pre-processing pipelines often include additional k-space filtering steps to mitigate these effects, such methods tend to incur further losses in an already insufficient spatial resolution. Another common approach is to refrain from exciting / refocusing the signal from known "nuisance" components during the acquisition through localization methods such as STEAM [1,2,3] or PRESS [4,5,6,7]. However, such techniques preclude the use of non-rectangular volumes of interest (VOIs), which may consequently exclude portions of the anatomy of interest as well.…”

Section: Introductionmentioning

confidence: 99%

Magnetic resonance spectroscopic imaging at superresolution: Overview and perspectives

Kasten

Klauser

Lazeyras

et al. 2016

Journal of Magnetic Resonance

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The notion of non-invasive, high-resolution spatial mapping of metabolite concentrations has long enticed the medical community. While magnetic resonance spectroscopic imaging (MRSI) is capable of achieving the requisite spatio-spectral localization, it has traditionally been encumbered by significant resolution constraints that have thus far undermined its clinical utility. To surpass these obstacles, research efforts have primarily focused on hardware enhancements or the development of accelerated acquisition strategies to improve the experimental sensitivity per unit time. Concomitantly, a number of innovative reconstruction techniques have emerged as alternatives to the standard inverse discrete Fourier transform (DFT). While perhaps lesser known, these latter methods strive to effect commensurate resolution gains by exploiting known properties of the underlying MRSI signal in concert with advanced image and signal processing techniques. This review article aims to aggregate and provide an overview of the past few decades of so-called "superresolution" MRSI reconstruction methodologies, and to introduce readers to current state-of-the-art approaches. A number of perspectives are then offered as to the future of high-resolution MRSI, with a particular focus on translation into clinical settings.

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Signal Intensities andT1 Calculations in Multiple-Echo Sequences with Imperfect Pulses

Kingsley

1999

Concepts Magn. Reson.

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Formulas are derived for longitudinal magnetization in multiple‐echo inversion recovery (IR), saturation recovery, and progressive saturation pulse sequences with imperfect pulses. The effects of imperfect pulses on the signal intensities and on the calculated T1 relaxation times are discussed. Relaxation data from all three methods can be fitted with an equation of the form: Signal intensity=[a+b exp(−TX/T1)]/[1+c exp(−TX/T1)], where TX is a variable delay time and the values of T1, a, b, and c are adjusted to optimize the fit. Only three parameters need to be fitted for progressive saturation with no echoes because b=−a. For modified fast IR (with constant repetition time TR), c=0 and a three‐parameter fit suffices even if several non–steady‐state signals are acquired and a range of flip angles is present within the sample. The advantages of the modified fast IR method for multiple‐slice measurements of T1 in magnetic resonance imaging (MRI) are reviewed. Other applications of these formulas include estimating errors in T1 calculations, finding the flip angles (“Ernst angles”), echo spacing, and TR that maximize the signal‐to‐noise ratio in multiple‐echo sequences, optimizing contrast between tissues in MRI, and determining how quickly a steady state is approached. ©1999 John Wiley & Sons, Inc. Concepts Magn Reson 11: 29–49, 1999

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Localized double spin echo proton spectroscopy part I: Basic concepts

Cited by 8 publications

References 12 publications

Single Volume Localization and Water Suppression

Single Volume Localization and Water Suppression

Magnetic resonance spectroscopic imaging at superresolution: Overview and perspectives

Signal Intensities andT1 Calculations in Multiple-Echo Sequences with Imperfect Pulses

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