“…4,24 Histologically, PVNS may appear as a broad sheet of histiocytes with scattered lymphocytes, lipid and hemosiderin-laden foam cells, and multinucleated giant cells (Figure 2). 2,8,17 The multinucleated giant cells and the foam cells distinguish PVNS from other arthropathies (Figure 3). 8 Radiographic evaluation of PVNS often depicts increased soft tissue density and can show bony erosions (Figure 4, A and 4, B).…”