2023
DOI: 10.3389/fendo.2023.1132172
|View full text |Cite
|
Sign up to set email alerts
|

Long-acting recombinant human follicle-stimulating hormone (SAFA-FSH) enhances spermatogenesis

Abstract: IntroductionAdministration of follicle-stimulating hormone (FSH) has been recommended to stimulate spermatogenesis in infertile men with hypogonadotropic hypogonadism, whose sperm counts do not respond to human chorionic gonadotropin alone. However, FSH has a short serum half-life requiring frequent administration to maintain its therapeutic efficacy. To improve its pharmacokinetic properties, we developed a unique albumin-binder technology, termed “anti-serum albumin Fab-associated” (SAFA) technology. We test… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
2
1

Relationship

0
3

Authors

Journals

citations
Cited by 3 publications
(1 citation statement)
references
References 34 publications
0
1
0
Order By: Relevance
“…4. Hormonal therapies: Hormonal treatments, including FSH and hCG, can boost sperm production in those with NOA, though their effectiveness varies by case [130].…”
Section: Testicular Sperm Extraction (Tese) Combined With Assisted Re...mentioning
confidence: 99%
“…4. Hormonal therapies: Hormonal treatments, including FSH and hCG, can boost sperm production in those with NOA, though their effectiveness varies by case [130].…”
Section: Testicular Sperm Extraction (Tese) Combined With Assisted Re...mentioning
confidence: 99%