Long-lasting allergic contact dermatitis to methylisothiazolinone misdiagnosed as atopic dermatitis

The Expert Panel for Cosmetic Ingredient Safety (Panel) reassessed the safety of Methylisothiazolinone, which functions as a preservative in cosmetics. The Panel reviewed relevant animal and human data provided in this safety assessment, and data from the previously published safety assessments of Methylisothiazolinone, and concluded that Methylisothiazolinone is safe for use in rinse-off cosmetic products at concentrations up to 100 ppm (ie, 0.01%) and safe in leave-on cosmetic products when they are formulated to be nonsensitizing, which may be determined based on a quantitative risk assessment or similar methodology.

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Long-lasting allergic contact dermatitis to methylisothiazolinone misdiagnosed as atopic dermatitis

Cited by 3 publications

References 6 publications

Contact Dermatitis: Classifications and Management

Contact Dermatitis: Classifications and Management

Toxin metalloproteinases exert a dominant influence on pro-inflammatory response and anti-inflammatory regulation in jellyfish sting dermatitis

Amended Safety Assessment of Methylisothiazolinone as Used in Cosmetics

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