2018
DOI: 10.1007/s11427-018-9337-0
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Long-lasting impairments in rodent oxygen-induced retinopathy measured by retinal vessel density and visual function

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Cited by 4 publications
(7 citation statements)
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“…As we reported in a previous paper, in the animals raised in 80% oxygen, the number of vessels extending into vitreous body increased and the retinal vessel density decreased (Wang et al, 2019). At the end of the 7-day treatment, the number of vessels extending into the vitreous body was significantly reduced (38.9%±4.3%), and the retinal vessel density significantly increased (superficial: 21.7%±4.6%, deep: 38.4%±11.7%).…”
Section: Alleviation Of Vascular Abnormalitiessupporting
confidence: 80%
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“…As we reported in a previous paper, in the animals raised in 80% oxygen, the number of vessels extending into vitreous body increased and the retinal vessel density decreased (Wang et al, 2019). At the end of the 7-day treatment, the number of vessels extending into the vitreous body was significantly reduced (38.9%±4.3%), and the retinal vessel density significantly increased (superficial: 21.7%±4.6%, deep: 38.4%±11.7%).…”
Section: Alleviation Of Vascular Abnormalitiessupporting
confidence: 80%
“…Our previous study provided a potential explanation. We found that there is a minimal level of vessel innervation, irrespective of exposing more immature retina by advancing initiation and lengthening exposure duration (Wang et al, 2019). When the high concentration of oxygen already suppressed the retinal vasculature to the minimal level, an increase in perfusion efficiency due to decreased IOP was unlikely to cause any further vessel loss, therefore further functional deterioration.…”
Section: Treating Rop By Reducing Iopmentioning
confidence: 70%
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