Long term clinical outcomes of patients with ischemic stroke in primary care – a 9-year retrospective study

Han, Jinghao; Choi, Yue Kwan; Leung, Wing; Hui, Ming; Leung, Maurice P.

doi:10.1186/s12875-021-01513-w

Cited by 5 publications

(4 citation statements)

References 29 publications

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“…In a Hong Kong study of 466 patients with ischemic stroke, a median follow-up period of 8.7 years, had a recurrent incidence of statin medication of 23.8%. The rate of statin medication in patients with non-recurrent cerebrovascular event is 43.5% [41]. It shows that the treatment rate of stroke patients in China needs to be improved.…”

Section: Discussionmentioning

confidence: 99%

Stroke Risk Factors of Stroke Patients in China: A Nationwide Community-Based Cross-Sectional Study

Chen

Zhu

et al. 2022

IJERPH

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Background: Stroke is the leading cause of death in China, and its burdens are rapidly increasing. The prevalence and control of stroke risk factors among stroke patients in China are unknown. Objective: We investigated the stroke risk factors of stroke patients in China. Design: We examined stroke risk factors in 6580 stroke patients aged 18 years or older in the China National Chronic Diseases and Nutrition Surveillance of Adults (2015–2017). With regard to the basic characteristics of the study participants, categorical variables were described as frequency (percent). The chi-square test was used to analyze the difference between men and women. The multivariate logistic regression model was used in the multivariate analysis. Results: Among the 6580 stroke patients, hypertension was the most common stroke risk factor identified in most cases (78.51%), followed by overweight or obesity (61.58%), dyslipidemia (54.38%), smoking (24.04%), diabetes (21.75%), family history of stroke (17.43%), lack of exercise (16.35%), and atrial fibrillation (4.47%). Drinking stroke patients had a lower rate of hypertension, diabetes, and dyslipidemia. Patients with hyperuricemia had a higher rate of hypertension and dyslipidemia than no-hyperuricemia patients. The hypertension awareness, treatment, and control rates among hypertension stroke patients were 73.62%, 70.19%, and 17.79%, respectively. The diabetes awareness, treatment, and control rates among diabetes patients were 69.74%, 65.83%, and 34.59%, respectively. The dyslipidemia awareness, treatment, and control rates among dyslipidemia patients were 42.37%, 29.4%, and 20.07%, respectively. Among treated hypertension patients, the rates of taking medicine as medically advised, controlled diet, increased exercise, and blood pressure monitoring were 91.31%, 58.88%, 45.78%, and 73.99%, respectively. Among treated diabetes patients, the rates of oral antidiabetic medications, insulin injection, diet control, and blood glucose monitoring were 78.24%, 34.71%, 85.77%, and 78.24%, respectively. Among treated dyslipidemic patients, the rate of taking medicine as medical advice, controlled diet, increased exercise, and regular blood lipid monitoring was 80.61%, 77.57%, 56.46%, and 40.3%, respectively. Conclusions: The most common risk factors for community stroke patients in China are hypertension, dyslipidemia, and overweight or obesity. The stroke community patients’ suboptimal awareness and treatment of hypertension, and suboptimal awareness, treatment, and control of diabetes, and dyslipidemia are significant problems in China.

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Section: Discussionmentioning

confidence: 99%

Stroke Risk Factors of Stroke Patients in China: A Nationwide Community-Based Cross-Sectional Study

Chen

Zhu

et al. 2022

IJERPH

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“…The National Institutes of Health Stroke Scale (NIHSS) was used to assess neurological status at admission. The severity of stroke was classified as moderate stroke (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15), moderate to severe (16)(17)(18)(19)(20), and severe stroke (≥21) using the NIHSS. Functional outcomes at discharge were assessed using the modified Rankin scale (mRS).…”

Section: Data Collectionmentioning

confidence: 99%

“…Compared to Western populations, Chinese people have a greater stroke incidence and mortality rate, as well as a higher level of disability-adjusted life years [3]. Strokes come in different forms, such as: subarachnoid hemorrhage, with a Diagnostics 2023, 13, 2298 2 of 13 frequency of around 5%; intracerebral hemorrhage, with 14%; and a majority of cases being ischemic stroke, constituting 80% of cases [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Brain-Derived Neurotrophic Factor (BDNF) and Translocator Protein (TSPO) as Diagnostic Biomarkers for Acute Ischemic Stroke

Tuwar,

Chen,

Chiwaya

et al. 2023

Diagnostics

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Brain-derived neurotrophic factor (BDNF) interacts with tropomyosin-related kinase B (TrkB) to promote neuronal growth, survival, differentiation, neurotransmitter release, and synaptic plasticity. The translocator protein (TSPO) is known to be found in arterial plaques, which are a symptom of atherosclerosis and a contributory cause of ischemic stroke. This study aims to determine the diagnostic accuracy of plasma BDNF and TSPO levels in discriminating new-onset acute ischemic stroke (AIS) patients from individuals without acute ischemic stroke. A total of 90 AIS patients (61% male, with a mean age of 67.7 ± 12.88) were recruited consecutively in a stroke unit, and each patient was paired with two age- and gender-matched controls. The sensitivity, specificity, and area of the curve between high plasma BDNF and TSPO and having AIS was determined using receiver operating characteristic curves. Furthermore, compared to the controls, AIS patients exhibited significantly higher levels of BDNF and TSPO, blood pressure, HbA1c, and white blood cells, as well as higher creatinine levels. The plasma levels of BDNF and TSPO can significantly discriminate AIS patients from healthy individuals (AUC 0.76 and 0.89, respectively). However, combining the two biomarkers provided little improvement in AUC (0.90). It may be possible to use elevated levels of TSPO as a diagnostic biomarker in patients with acute ischemic stroke upon admission.

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“…Likewise, Chen, et al (2022) finalized that "the stroke community patients' suboptimal awareness and treatment of hypertension, control of diabetes, and dyslipidemia are significant problems in China". Uniformly, the most common risk factors for community stroke patients in China are hypertension, dyslipidemia, and overweight or obesity (Han, Choi, Leung, Hui, & Leung, 2020). In addition, Shah, et al (2013) confer that "hypertension, smoking, diabetes, sedentary lifestyle and cardiac problems have strong correlations and association with stroke and are the major risk factors.…”

Section: Literature Reviewmentioning

confidence: 99%

Awareness Status of Stroke among the Students of Saraswati Multiple Campus: An Exploratory Study

Adhikari,

Malla

2023

Nep. J. Multidisc. Res.

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Stroke is a cerebrovascular disease characterized as a medical emergency that occurs when a blockage ensues in the brain and the blood supply is interrupted or discontinued by any means. It is popularly categorized as Ischemic stroke, Intracranial Hemorrhage, and Subarachnoid Hemorrhage and is one of the leading cause of deaths worldwide. This research includes prevention techniques, treatment strategies, opinions, and the awareness status of respondents, sequentially including the citations of various researchers on the issue of stroke. The research explores stroke-associated factors and the awareness status among the students, who are currently pursuing the degree, Master of Arts in Sociology and English at Saraswati Multiple Campus, Tribhuvan University. Similarly, the number of respondents was 22, and the data was collected through a convenience sampling technique that demonstrates the opinions of the respondents. The researcher has used both qualitative and quantitative methods to analyze the data. The principal findings present that the respondents (40.91%) believes hypertension is the major factor in stroke, whereas respondents (54.5%) agrees that exercise and healthy lifestyle modification can reduce the risk factors. Correspondingly, the data concludes respondents (86.4%) takes the stroke patient to the hospital and shows the overall awareness status is satisfactory. Furthermore, the knowledge in the event of stroke contribution to the patient is strong and the respondents (77.3%) have stated that the stroke affects the brain, although they are not familiar with Cardiopulmonary Resuscitation (CPR) techniques if the patient is in unconscious condition having breathing problem. Finally, the research concludes that stroke awareness status is satisfactory among the respondents and prioritizes that stroke-related course books must be included at the University level of Social Sciences disciplines, whereby the proper information and knowledge spreads within the students. It improves on identifying the actual symptoms and also encourages the patient's early admission to the hospital, which helps to decrease disability and other impairments via conducting proper methods.

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Long term clinical outcomes of patients with ischemic stroke in primary care – a 9-year retrospective study

Cited by 5 publications

References 29 publications

Stroke Risk Factors of Stroke Patients in China: A Nationwide Community-Based Cross-Sectional Study

Stroke Risk Factors of Stroke Patients in China: A Nationwide Community-Based Cross-Sectional Study

Brain-Derived Neurotrophic Factor (BDNF) and Translocator Protein (TSPO) as Diagnostic Biomarkers for Acute Ischemic Stroke

Awareness Status of Stroke among the Students of Saraswati Multiple Campus: An Exploratory Study

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