Long-term effects of whole body cryostimulation on uric acid concentration in plasma of secondary progressive multiple sclerosis patients

Abstract

WBCT may be used as adjuvant therapy via increase UA blood level; it improves functional status of SPMS patients.

Whole-body cryostimulation (cryotherapy) provides benefits for fatigue and functional status in multiple sclerosis patients. A case-control study

“…Patients with MS were exposed 10 times to WBC (one exposure each day) as previously described . This occurred in a cryogenic chamber and was carried out daily from Monday to Friday.…”

“…Recently, we have shown a significant and positive impact of a series of 10 sessions of WBC in MS patients with neurological deficits (muscle strength increase, decreased spasticity, disability reduction, and a higher level of antioxidative status) . However, the impact of WBC on functional status (physical and psychological aspects) and quality of life in MS patients with fatigue syndrome is unknown .…”

The Impact of Health Resort Treatment on the Nonenzymatic Endogenous Antioxidant System

“…As demonstrated in studies conducted by Miller and Kedziora, plasma levels of uric acid and total systemic antioxidative potential increased following a series of 10 cryotherapy sessions in multiple sclerosis patients. The author believes that by increasing the total systemic antioxidative potential including the uric acid level, cryotherapy may constitute a supplementary treatment in MS patients [37]. This conclusion surely warrants further studies and observations.…”

Effect of whole-body cryotherapy treatments on the functional state of patients with MS (multiple sclerosis) in a Timed 25-Foot Walk Test and Hand Grip Strength Test

“…In recent years, WBC has become a physical treatment increasingly used in rehabilitation [21]. There are a number of studies that demonstrate the benefits of its use in the course of various diseases, including patients with MS. Studies describing the positive effect of WBC on MS patients focus, among others, on changes in the physicochemical parameters of the blood, or reductions in oxidative stress [12,13,14,15,16]. When analysing available literature, a number of studies can be found that indicate the beneficial effects of frequent WBC in biological renewal -improving muscle strength, faster muscle recovery after exercise, improved cardiovascular and hormonal systems, better lipid changes in the body, and many others factors showing an improved functional status of the body [22,23,24,25].…”

“…arthritis, fibromyalgia, depression) [11]. Numerous studies have also shown the positive effects of WBC in an increase in muscle strength, reduction of spasticity, increase of antioxidant activity in the body, reduction of disability among patients with neurological symptoms [12,13,14,15,16]. In recent years, WBC has become very popular and is now one of the main elements of comprehensive rehabilitation of patients with MS [17].…”