Long-term follow-up of ciliated muconodular papillary tumor of the lung by computed tomography: a case report

Abstract

Ciliated muconodular papillary tumor (CMPT) is an extremely rare pulmonary tumor and the clinical characteristics are still unknown. We report the preoperative long-term clinical course and changes in computed tomography (CT) findings of CMPT. A 60-year-old man underwent lower bilobectomy for squamous cell carcinoma in the right lower lobe 18 years before the surgery for CMPT. Twelve years before the surgery for CMPT, a 4-mm small ground glass nodule arose in the left lower lobe. The nodule gradually grew and became dense over time. Because it became mostly solid with central cavities, the patient underwent wedge resection and the tumor was diagnosed as CMPT. There were no recurrences 20 months after surgery. The preoperative CT findings of CMPT were similar to progressive preinvasive lesion, whereas it followed the benign clinical course. To the best of our knowledge, this is the first report on long-term preoperative follow-up of CMPT.

Ciliated muconodular papillary tumor of the lung with cavitary change: A case report with 11‐year preoperative follow‐up

“…In the case of a patient with 12 years of follow-up reported in 2020, the tumor initially appeared as a ground-glass nodule, then increased in density to become a solid nodule and a central cavity eventually developed. 15 Similarly, in this case, a central cavitary change was observed in the solid nodule during the follow-up period. In the present case, the tumor had abundant mucous lakes, and as the tumor grew, the mucous lakes formed the central cavity.…”

“…To the best of our knowledge, there has been only one case of long‐term preoperative follow‐up that showed the natural course of the tumor. In the case of a patient with 12 years of follow‐up reported in 2020, the tumor initially appeared as a ground‐glass nodule, then increased in density to become a solid nodule and a central cavity eventually developed 15 . Similarly, in this case, a central cavitary change was observed in the solid nodule during the follow‐up period.…”

“… 4 Internal cavities have been reported in a few cases, and mucous lakes are likely to be found as cavities. 13 , 14 , 15 , 16 CMPTs show no or moderate increase in FDG uptake on PET/CT. 17 …”

“…4 Internal cavities have been reported in a few cases, and mucous lakes are likely to be found as cavities. [13][14][15][16] CMPTs show no or moderate increase in FDG uptake on PET/CT. 17 CMPT is a slow-growing tumor, but little is known about its growth rate.…”

“…CMPTs presenting as ground‐glass nodules contain more mucin than those presenting as solid nodules 4 . Internal cavities have been reported in a few cases, and mucous lakes are likely to be found as cavities 13–16 . CMPTs show no or moderate increase in FDG uptake on PET/CT 17 …”