Long-Term Followup of Primary Nonrefluxing Megaureter

Renzo, Dacia Di; Aguiar, Liza; Cascini, Valentina; Nicola, Marta Di; McCarten, Kathleen; Ellsworth, Pamela; Chiesa, Pierluigi Lelli; Caldamone, Anthony A.

doi:10.1016/j.juro.2013.03.008

Cited by 50 publications

(29 citation statements)

References 20 publications

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“…Fieberhafte Harnwegsinfektionen treten bei Kindern mit Megaureter häufiger auf als bei Gesunden (47 % vs. 13 %) [13]. Besonders betroffen sind Säuglinge mit einem obstruktiven Harnabflussverhalten in der Diureseszintigrafie [9]. Darüber hinaus scheint der Grad der Nierenbeckenkelchdilatation mit dem Infektionsrisiko zu korrelieren.…”

Section: Behandlungunclassified

Der Primär Obstruktive Megaureter (POM) – Eine Domäne konservativer Therapie

Stehr

Schäfer

2019

Aktuel Urol

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ZusammenfassungDer Begriff „Megaureter“ ist eine rein deskriptive Bezeichnung einer Reihe von Krankheitsentitäten. Entscheidend ist, ob der Megaureter primär oder sekundär auftritt oder ob er obstruktiv und/oder refluxiv ist. Häufig liegt eine primäre Obstruktion im Bereich des ureterovesikalen Übergangs vor. Die Therapie des primär obstruktiven Megaureters hat sich in den letzten 30 Jahren deutlich gewandelt. Wurde früher in der Mehrzahl der Fälle eine Ureterreimplantation durchgeführt, werden heute 85 – 90 % der Patienten konservativ behandelt. Neben der Reimplantation steht mit der Ballondilatation ein modernes, minimal-invasives Verfahren zur Verfügung, das ist ausgewählten Fällen zu einem Benefit für den Patienten führen kann. Da es aufgrund der Möglichkeit eines postoperativ auftretenden VUR gleichwohl nicht komplikationslos ist, muss betont werden, dass die Verfügbarkeit dieses neuen Verfahrens die generell strenge Indikation zur Operation des Pirimär Obstruktiven Megaureters nicht aufweichen sollte.

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Section: Behandlungunclassified

Der Primär Obstruktive Megaureter (POM) – Eine Domäne konservativer Therapie

Stehr

Schäfer

2019

Aktuel Urol

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“…Antibiotic prophylaxis can be indicated in infants with a primary obstructive megaureter during the first six months of life because there is a higher risk of complications due to pyelonephritis (Anheuser et al 2013). Most cases of primary megaureter (PM) resolve spontaneously, but long-term follow-up is recommended because symptoms can develop years later (Di Renzo et al 2013). A high rate of spontaneous resolution of or decrease in urinary tract dilatation is expected for most cases.…”

Section: Primary Megauretermentioning

confidence: 99%

Kidney, Urinary Bladder, and Ureter

Ardalan

2016

Bergman's Comprehensive Encyclopedia of Human Anatomic Variation

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“…[1][2][3][4][5][6] The percentage of children in need of surgery ranges from 23 to 30% in various articles in the literature. [7][8][9][10] We have previously published that risk factors, which might require surgical correction were Society for Fetal Urology (SFU) grades 3 and 4 of postnatal hydronephrosis, relative renal function less than 30%, and ureteral diameter more than 1.33 cm. 10 The good short-and midterm results after ureter reimplantation with regard to the improvement or preservation of renal function are well described before, even in poorly Introduction Ureteric reimplantation due to ureterovesical junction (UVJ) obstruction enjoys high success in the short term.…”

Section: Introductionmentioning

confidence: 99%

Does Renal Function Remain Stable after Puberty in Children who underwent Ureteral Reimplantation due to Ureterovesical Junction Obstruction?

et al. 2020

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Introduction Ureteric reimplantation due to ureterovesical junction (UVJ) obstruction enjoys high success in the short term. However, renal function after reimplantation must accommodate the numerous changes in the pediatric urinary tract that occur along with child development that may theoretically cause an occult loss of renal function. The purpose of this study was to evaluate whether improved renal function after ureter reimplantation for antenatal diagnosed UVJ obstruction remains stable after puberty. Materials and Methods Twenty-one children who underwent open reimplantation using Politano–Leadbetter technique were followed until they completed puberty. Mean age at surgery was 14.3 months (range: 3–60 months). Five (23.8%) of 21 children had right hydronephrosis, 13 (61.9%) had left hydronephrosis, and 3 (14.3%) had bilateral hydronephrosis. The Society for Fetal Urology (SFU) level of the hydronephrosis was 3 (47.6%) in 10 children and 4 (52.4%) in remaining 11. Fourteen (66.6%) patients had poor renal function upon surgery and the remaining seven (33.4%) patients had moderate renal function. The mean renal function upon operation was 28 ± 4.3 (mean ± standard deviation [SD]). Results Reimplantation led to the increase in the RRF in the short-term period from 28 ± 4.3% prior to the surgery to 36.4 ± 5% (p < 0.001) in all patients and remains stable 35 ± 5% after puberty in all the reviewed patients. Conclusion Our data demonstrate for the first time that successful ureteral reimplantation following antenatal diagnosis of UVJ obstruction is associated with an improvement in renal function, not only during short- and midterm follow-up but also allows preserving the renal function throughout the puberty period.

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Long-Term Followup of Primary Nonrefluxing Megaureter

Cited by 50 publications

References 20 publications

Der Primär Obstruktive Megaureter (POM) – Eine Domäne konservativer Therapie

Der Primär Obstruktive Megaureter (POM) – Eine Domäne konservativer Therapie

Kidney, Urinary Bladder, and Ureter

Does Renal Function Remain Stable after Puberty in Children who underwent Ureteral Reimplantation due to Ureterovesical Junction Obstruction?

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