Long-Term Improvement in Coping Skills Following Multimodal Treatment in War Veterans with Chronic PTSD

Britvić, Dolores; Glučina, Dubravka; Antičević, Vesna; Kekez, Vesna; Lapenda, Branka; Đogaš, Varja; Dodig, Goran; Urlić, Ivan; Moro, Iva Nemčić; Frančišković, Tanja

doi:10.1521/ijgp.2012.62.3.418

Cited by 5 publications

(5 citation statements)

References 20 publications

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“…Perhaps the best grounds for proposing that a 5-HT dysfunction exists in PTSD resides in the beneficial treatment effects of SSRIs, which, to date, have already been established as the first-line pharmacotherapeutic agents for treating acute and chronic PTSD. However, SSRIs largely have disadvantages including delayed onset of action, partial response with residual symptoms or non-response, and severe side effects (e.g., loss of sexual drive, gastrointestinal effects, changes in body weight), which limit their utility and indicate a major unmet medical need to explore more promising treatment approaches in PTSD [11–17]. …”

Section: Introductionmentioning

confidence: 99%

Anxiolytic Effects of Flavonoids in Animal Models of Posttraumatic Stress Disorder

Zhang¹,

Yao²,

Li³

et al. 2012

Evidence-Based Complementary and Alternative Medicine

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The dysregulation of the serotonergic system has long been recognized as an important factor underlying the pathophysiology of PTSD. To date, SSRIs have already been established as the firstline pharmacotherapeutic agents for treating acute and chronic PTSD. However, SSRIs largely have several disadvantages which limit their utility. Our previous study has also shown that administration of the total flavonoids, isolated from the extract of Xiaobuxin-Tang (XBXT, mild mind-easing decoction), comprising four Chinese medicines including Haematitum, Flos Inulae, Folium Phyllostachydis Henonis, and Semen Sojae Preparatum, exerted significant antidepressant-like effect in chronically mildly stressed rats, possibly mediated by serotonergic activation. Since the central serotonergic dysfunction is an important and well-known cause mediating the pathophysiology of trauma-related symptoms in PTSD, it is reasonable to predict that flavonoids may exert therapeutic effects on PTSD in animal models. Therefore, the present study aims to examine the effect of flavonoids in alleviating the enhanced anxiety and fear response induced in two PTSD animal models. Ser, an SSRI, was administered as a positive control. Furthermore, the changes of brain monoaminergic neurotransmitters after chronic flavonoids administration have also been assessed in SPS-treated rats.

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Section: Introductionmentioning

confidence: 99%

Anxiolytic Effects of Flavonoids in Animal Models of Posttraumatic Stress Disorder

Zhang¹,

Yao²,

Li³

et al. 2012

Evidence-Based Complementary and Alternative Medicine

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“…Neither sampled U.S. military veterans nor included control groups. Britvic ́et al (2012) observed significant reductions in PTSD and depression posttreatment in a sample of Croatian veterans, but gains were not maintained at follow-up. The dropout rate in this study was 17%.…”

Section: Mmgts For Ptsdmentioning

confidence: 88%

Feasibility of multimodal group treatment for veterans with PTSD, depression, and high-risk drinking: A pilot study.

Liese¹,

Monley²

2023

Journal of Psychotherapy Integration

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U.S. military veterans experience a wide range of postdeployment psychological problems, including disproportionate rates of posttraumatic stress disorder (PTSD), depression, and high-risk drinking. First-line psychological treatments for these conditions (e.g., cognitive-behavioral therapy) are effective but can be lengthy and intensive, leading many veterans to drop out of treatment. A novel brief multimodal group treatment (MMGT) program has been developed as an alternative to these first-line treatments. It was hoped that this brief treatment would exhibit lower dropout compared to lengthier first-line treatments, while still helping veterans learn emotion-regulation and interpersonal skills to reduce symptoms of PTSD, depression, and high-risk drinking. Cohorts of up to 18 group members meet for this 5-day program that integrates cognitive-behavioral instruction, mindfulness practice, and emotion-focused principles into didactic and experiential group activities. For several years pretreatment and posttreatment follow-up data have been collected from group members, including symptoms of moral injury, posttraumatic stress, depression, and high-risk drinking. We report pilot data from 50 veterans who participated in this program and completed a posttreatment follow-up survey and program evaluation. Scores on measures of posttraumatic stress, depression, and high-risk drinking were significantly reduced at posttreatment follow-up. The dropout rate for this program (2.9%) was lower than veterans’ average dropout rate across all types of PTSD treatment (36%). Veterans’ perceptions of the program are discussed. Based on these findings, we discuss implications for working with veterans in brief MMGTs and conducting research on these interventions.

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“…Training in trauma-focused CBT and EMDR is offered to practitioners, but this is not fully integrated into the helping system. With the existing high level of competencies in dynamic psychotherapy and psychopharmacology (Britvić et al, 2012), the challenge remains to develop a more stepwise approach to trauma-informed services, increase public awareness of risk and resilience factors, and to expand treatment choices to include evidencebased trauma-focused therapies and make them more available to the general populations in need. The Croatian Society for Traumatic Stress (CSTS) has been working on this challenge since it was founded in 2011 by organizing training workshops.…”

Section: Psychotraumatology In Croatiamentioning

confidence: 99%

Trauma and trauma care in Europe

Schäfer

Hopchet²,

Vandamme³

et al. 2018

European Journal of Psychotraumatology

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The European countries have a long history of exposure to large-scale trauma. In the early 1990s the increasing awareness of the consequences of trauma within the mental health community led to the foundation of local societies for psychotraumatology across Europe and the European Society of Traumatic Stress Studies (ESTSS), which celebrated its 25th anniversary in 2018. The focus of this article is to describe the current state of care for survivors of trauma in the 15 European countries where ESTSS member societies have been established. Brief descriptions on the historical burden of trauma in each country are followed by an overview of the care system for trauma survivors in the countries, the state-of-the-art of interventions, current challenges in caring for survivors and the topics that need to be most urgently addressed in the future. The reports from the different countries demonstrate how important steps towards a better provision of care for survivors of trauma have been made in Europe. Given the cultural and economic diversity of the continent, there are also differences between the European countries, for instance with regard to the use of evidence-based treatments. Strategies to overcome these differences, like the new ESTSS training curricula for care-providers across Europe, are briefly discussed.

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Long-Term Improvement in Coping Skills Following Multimodal Treatment in War Veterans with Chronic PTSD

Cited by 5 publications

References 20 publications

Anxiolytic Effects of Flavonoids in Animal Models of Posttraumatic Stress Disorder

Anxiolytic Effects of Flavonoids in Animal Models of Posttraumatic Stress Disorder

Feasibility of multimodal group treatment for veterans with PTSD, depression, and high-risk drinking: A pilot study.

Trauma and trauma care in Europe

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