2015
DOI: 10.1016/j.aap.2015.09.011
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Long term mortality in a population-based cohort of adolescents, and young and middle-aged adults with burn injury in Western Australia: A 33-year study

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Cited by 36 publications
(20 citation statements)
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“…The project was approved by the Human Research Ethics Committees of the University of Western Australia and the Western Australian Department of Health and project methods and analyses have been previously published [7, 23]. …”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…The project was approved by the Human Research Ethics Committees of the University of Western Australia and the Western Australian Department of Health and project methods and analyses have been previously published [7, 23]. …”
Section: Methodsmentioning
confidence: 99%
“…Advances in medical management in recent years have resulted in significant declines in hospital mortality,[5, 6]. However, population-based research has shown burn survivors experience decreased long-term survival [7, 8], whilst increased long-term morbidity has been shown both in population studies and other models of burn injury [911]. …”
Section: Introductionmentioning
confidence: 99%
“…The project methodology has been reported previously. 22,30 WADLS staff provided a de-identified extraction of hospital records for individuals <5 years of age when admitted to a hospital in Western Australia with a first burn between January 1, 1980 and June 30, 2012 by using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes 940-949 or International Classification of Diseases, Tenth Revision, Australian Modification (ICD-10-AM) codes T20-T31. A first (index) burn injury was defined as the first hospital admission with a burn identified as the principal or additional diagnosis.…”
Section: Methodsmentioning
confidence: 99%
“…18 Systemic effects of severe burns are well documented and have been shown to persist for up to 3 years 19,20 ; however, recent evidence indicates longer-term immune dysfunction after both severe and minor burns. 21 Population-based research has identified long-term postburn cardiovascular 22,23 and musculoskeletal morbidity, 24,25 as well as increased incidence of cancers, 26,27 after severe and minor burns. Although the underlying mechanisms are not clear, postburn morbidity suggests persistent effects of acute inflammatory and immune system responses after wound healing.…”
mentioning
confidence: 99%
“…While recent animal-based research indicates long-term immune dysfunction after non severe burn injury [15], to date the effect of severe and less severe burn injury on the long-term function of the immune system has not been comprehensively investigated. Initial investigations of long-term morbidity after burn injury using population-based data have identified increased post-burn circulatory morbidity, after both minor and severe burns [16], suggesting a substantial acute inflammatory response [15], as well as increased incidence of some types of cancers [17,18], suggesting long-term effects of burns on the immune system.…”
Section: Introductionmentioning
confidence: 99%