In the ocean depth detection, the multi-beam detection technology is widely used. Compared with the traditional singlebeam sounding system, multi-beam detection can obtain the seabed depth value of multiple measurement points in a stripcovered area, thus improving the accuracy of ocean depth measurement. This paper mainly studies the beam coverage and measurement efficiency of multi-beam detection in the submarine slope, and solves the optimization work based on the sinusoidal theorem and trust domain solution method, which is helpful for multi-beam detection technology in submarine topographic survey, submarine geophysical exploration, submarine pipeline detection and other fields.