The Journal of the Association for Information Science & Technology (JASIST) is a leading information science journal, recognized by many ranking metrics. Understanding patterns in articles published would be helpful to new researchers seeking to publish with the journal. However, the last comprehensive bibliometric analysis on JASIST is more than a decade old. The objective of this paper is to analyze the bibliographic information of full‐length research articles published in JASIST during the last two decades. This includes metrics such as article count, authorship, international collaboration, citations, and topical areas. Data was collected from SCOPUS, JASIST website, and Scimago. The findings show that JASIST published 3,052 articles during 2000–2020, which got cited 180,608 times (59.18 times per article) to date. Joint authorship and international collaboration has been increasing. Authors from institutions in 70 countries have published, with most articles from USA, with authorship from China steadily increasing in recent years. The detailed findings in the paper would help information science researchers and practitioners to assess the areas of focus, and various patterns in a top journal of the field. Such historical understanding is critical in charting agendas and directions for future research.