Long-term prognosis of patients with life-threatening ventricular arrhythmias induced by coronary artery spasm

Rodríguez‐Mañero, Moisés; Olóriz, Teresa; Waroux, Jean-Benoît le Polain de; Burri, Haran; Kreidieh, Bahij; Asmundis, Carlos de; Arias, Miguel Á.; Arbelo, Elena; Fernández, Brais Díaz; Fernández-Armenta, Juan; Basterra, Nuria; Izquierdo, María; Dı́az-Infante, Ernesto; Ballesteros, Gabriel; López, Andrés Carrillo; García‐Bolao, Ignacio; Bénézet-Mazuecos, Juan; Expósito-García, Víctor; Larraitz-Gaztañaga,; Martínez‐Sande, Luis; García‐Seara, Javier; González-Juanatey, José Ramón; Peinado, Rafaél

doi:10.1093/europace/eux052

Cited by 46 publications

(44 citation statements)

References 13 publications

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“…Similarly, another study also demonstrated high risk of recurrent ventricular arrhythmias in patients with ASCA secondary to VSA despite medical therapy. Thus, ICD may be protective, especially in this high-risk group of patients with ASCA [7].…”

Section: Discussionmentioning

confidence: 99%

Refractory Vasospastic Angina and Sudden Cardiac Arrest: Is Implantable Cardioverter Defibrillator Indicated and Is It Always Protective?

Riaz

Raj

Shah

2020

Cureus

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Vasospastic angina (VSA) is characterized by episodic chest pain associated with transient STsegment abnormalities on electrocardiogram, secondary to vasospasm of the epicardial coronary artery. We report the rare case of a 46-year-old female with refractory VSA secondary to multivessel coronary vasospasm causing an anterior myocardial infarction. She succumbed secondary to ventricular tachycardia (VT) storm, in spite of being on maximally tolerated medical therapy and having an implantable cardioverter defibrillator (ICD) for secondary prevention of VT. Contemporary guidelines recommend ICD implantation (class IIa) in VSA patients who survived sudden cardiac arrest (SCA), if they are already on optimal medical therapy or if medical therapy is not tolerated. Whether ICD implantation is appropriate in VSA patients with aborted SCA, even before assessing the response to medical therapy, is not well known and requires further studies.

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Section: Discussionmentioning

confidence: 99%

Refractory Vasospastic Angina and Sudden Cardiac Arrest: Is Implantable Cardioverter Defibrillator Indicated and Is It Always Protective?

Riaz

Raj

Shah

2020

Cureus

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“…However, for some VSA patients, taking a CCB at the time of rising may be effective. In addition, we may add another vasodilator such as long-acting nitrates, nicorandil and other types of CCBs (dihydropyridine CCB vs non-dihydropyridine CCB)[ 12 ]. Finally, as shown in the present case reports, we must check whether the prescribed vasodilators are brand-name vasodilators or not.…”

Section: Discussionmentioning

confidence: 99%

Increased frequency of angina attacks caused by switching a brand-name vasodilator to a generic vasodilator in patients with vasospastic angina: Two case reports

Goto-Semba¹,

Fujii²,

Ueda³

et al. 2018

WJC

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It is well known that calcium channel blockers (CCBs) are the first line of therapy for vasospastic angina (VSA). Here, we report two cases of VSA with an increase in the frequency of angina attacks after switching from a brand-name to a generic CCB. In both cases, angina recurred upon switching from a brand-name CCB to a generic CCB during follow-up. The patients’ condition improved upon switching back to the original CCB. Both cases involved a high severity of VSA, based on the results of spasm provocation testing. These findings suggest that, in some patients with severe VSA, the frequency of angina attacks increases when switching from a brand-name CCB to a generic CCB. Cardiologists should consider this factor when prescribing drugs for angina.

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“…Second, the need for ICD in VSA patients with cardiac arrest has been one of the unsolved problems of coronary spasm[ 28 , 32 , 56 , 79 , 80 ]. Recently, Sueda et al[ 32 ] have summarized the results that appropriate ICD shocks were observed in 24.1% of VSA patients with aborted ICD.…”

Section: Uncertain or Unsolved Problems Regarding Coronary Spasmmentioning

confidence: 99%

“…Recently, Sueda et al[ 32 ] have summarized the results that appropriate ICD shocks were observed in 24.1% of VSA patients with aborted ICD. Rodríguez-Mañero et al[ 80 ] have shown that ICD was effective when insufficient medications were administered in VSA patients. In the clinical setting, whether sufficient medications without ICD can prevent such malignant arrhythmia due to coronary spasm is still undetermined.…”

Section: Uncertain or Unsolved Problems Regarding Coronary Spasmmentioning

confidence: 99%

Coronary spasm: It’s common, but it’s still unsolved

Teragawa¹,

Oshita²,

Ueda³

2018

WJC

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Coronary spasm is caused by a transient coronary narrowing due to the constriction of epicardial coronary artery, which leads to myocardial ischemia. More than 50 years have passed since the first recognition of coronary spasm, and many findings on coronary spasm have been reported. Coronary spasm has been considered as having pivotal roles in the cause of not only rest angina but also exertional angina, acute coronary syndrome, and heart failure. In addition, several new findings of the mechanism of coronary spasm have emerged recently. The diagnosis based mainly on coronary angiography and spasm provocation test and the mainstream treatment with a focus on a calcium-channel blocker have been established. At a glance, coronary spasm or vasospastic angina (VSA) has become a common disease. On the contrary, there are several uncertain or unsolved problems regarding coronary spasm, including the presence of medically refractory coronary spasm (intractable VSA), or an appropriate use of implantable cardioverter defibrillator in patients with cardiac arrest who have been confirmed as having coronary spasm. This editorial focused on coronary spasm, including recent topics and unsolved problems.

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Long-term prognosis of patients with life-threatening ventricular arrhythmias induced by coronary artery spasm

Cited by 46 publications

References 13 publications

Refractory Vasospastic Angina and Sudden Cardiac Arrest: Is Implantable Cardioverter Defibrillator Indicated and Is It Always Protective?

Refractory Vasospastic Angina and Sudden Cardiac Arrest: Is Implantable Cardioverter Defibrillator Indicated and Is It Always Protective?

Increased frequency of angina attacks caused by switching a brand-name vasodilator to a generic vasodilator in patients with vasospastic angina: Two case reports

Coronary spasm: It’s common, but it’s still unsolved

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