Long-term results of national treatment trials in childhood acute lymphoblastic leukaemia in several Middle/East European countries

Treatment results for children and adolescents with acute myeloid leukemia in Middle and Eastern European countries

“…In Middle and Eastern Europe, the standards of medical care have improved since 1990. However, overall, the standardized, risk-adapted treatment regimens according to multicenter protocols, for example as developed by the Berlin-Frankfurt-Muenster (BFM)-Study Group for treatment of childhood ALL (ALL IC-BFM 2002 trial [2]), is not yet a routine approach for the management of AML in Middle or Eastern Europe. Despite a relatively good standard of general pediatric care in some of these countries, one of the underlying problems so far has been that the pediatric oncology frequently suffered from lack of financial resources not only for research and specific diagnostic procedures but also and most importantly for the costly treatment such as anticancer drugs, antibiotics, etc.…”