Long-term survival of living donor renal transplants: A single center study

Abstract

Kidney transplantation is the treatment of choice for end-stage renal disease. The aim of this study was to determine the ten-year graft survival rate of renal transplantation in patients who have been transplanted from live donors. This is a historical cohort study designed to determine the organ survival rate after kidney transplantation from live donor during a 10-year period (from March 1999 to March 2009) on 843 patients receiving kidney transplant in the transplantation center of Namazi hospital in Shiraz, Iran. Kaplan-Meier method was used to determine the survival rate, log-rank test was used to compare survival curves, and Cox proportional hazard model was used to multivariate analysis. Mean follow-up was 53.07 ± 34.61 months. Allograft survival rates at 1, 3, 5, 7, and 10 years were 98.3, 96.4, 92.5, 90.8, and 89.2%, respectively. Using Cox proportional hazard model, the age and gender of the donors along with the creatinine level of the patients at discharge were shown to have a significant influence on survival. The 10-year graft survival rate of renal transplantation from living donor in this center is 89.2%, and graft survival rate in our cohort is satisfactory and comparable with reports from large centers in the world.

Paid Donation: A Global View

“…The policy of “no questions asked” prior to LURD KT should be replaced by a mandatory waiting period, as required in Shiraz. This has led to a significant increase in DD and LRD transplantations 5 . In conclusion , the pioneers in Iran should be commended for developing a unique model during a period of post-revolution, war and sanctions.…”

“…The number of DD transplants has increased at disappointingly slow pace, with the majority being performed in Shiraz 3 . Whereas nationally DD KTs account for 5–10% of the total annual KTs 21,22 review of 10-year data from Shiraz shows that from 1355 KTs, 38% were from DDs 5 . Also, while only 15% of KTs in Iran are from LRDs 23 , 30% of KTs from Shiraz are from LRDs 5 .…”

Survival Rate of Living Related Kidney Transplant Patients in Surabaya

“…In 2010, the survival rate of kidney transplant patients in Iran for 1, 3, and 5 years after surgery were 98.5%, 96.4%, and 92.5%. 8 The high survival rate for kidney transplant patients is influenced by a multitude of factors such as the advancement of surgical procedures, minimum cold ischemia time, and the development of immunosuppressive therapies. 9 The observation of kidney transplant survival rate is conducted after three months post-surgery, due to the high risk of complications in the said period of time.…”

The Relationship between Health Literacy and General Health Level of Hemodialysis Patients: A Case Study in Iran

“…The prevalence rate of chronic renal failure in the world is 242 cases per one million of the population, and this population annually increases by eight percent (3). In Iran, the prevalence and incidence of advanced renal failure in 2010 were, respectively, reported to be 357 and 57 cases per one million people over one year (4). Therefore, hemodialysis is the most common alternative treatment in the final stage of renal disease (5).…”