Longitudinal EEG and clinical study of children with febrile convulsions

Frantzen, E; Lennox-Buchthal, Margaret A.; Nygaard, A

doi:10.1016/0013-4694(68)90001-1

Cited by 139 publications

(74 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Predominantly posterior background abnormalities were reported in as many as a third of the patients, generally within the first week after the seizure, and best appreciated in the awake EEG (1,9). The absence of reported posterior slowing in our patients may be related to our practice of obtaining sleep and often sedated inducedsleep EEG recordings in this population.…”

Section: Discussionmentioning

confidence: 99%

“…Such a wide difference is due in part to the definition of the EEG abnormalities, the time elapsed from the febrile seizure, and the age of the patient at the time of the EEG (1,2,4). No published study has demonstrated that an EEG performed either at the time of presentation after a simple FS or within the following month will predict the occurrence of future afebrile seizures (5).…”

mentioning

confidence: 99%

“…The reported incidence of EEG abnormalities in children with febrile seizures (FS) varies from 2 to 86% (1)(2)(3). Such a wide difference is due in part to the definition of the EEG abnormalities, the time elapsed from the febrile seizure, and the age of the patient at the time of the EEG (1,2,4).…”

mentioning

confidence: 99%

See 2 more Smart Citations

The Value of Early Postictal EEG in Children with Complex Febrile Seizures

et al. 2000

View full text Add to dashboard Cite

Summary:Purpose: To assess the usefulness of an early postictal EEG in neurologically normal children with complex febrile seizures.Methods: We conducted a retrospective chart review of all neurologically normal children who were hospitalized over a period of 2.5 years after complex febrile seizures, and had an EEG up to 1 week after the seizure.Results: Thirty-three patients (mean age, 17.8 months) qualified for inclusion into the study. Twenty-four patients were qualified as complex cases based on one factor (prolonged in 9, repetitive in 13, and focal in 2). Nine other patients had two complex factors: in six patients, the seizures were long and repetitive; in two patients, the seizures were focal and repetitive; and in one patient, the seizures were long, focal, and repetitive. Thirteen (39%) patients experienced prior febrile seizures. All 33 patients had a normal postictal sleep EEG. Our results indicate with a 95% probability that the true rate of abnormalities in an early postictal EEG performed on otherwise normal children with complex febrile seizures is 8.6% or less.Conclusions: The yield of abnormalities of an early postictal EEG in this population is low and similar to the reported rate of abnormalities in children with simple febrile seizures. The routine practice of obtaining an early EEG in neurologically normal children with complex febrile seizures is not justified.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

The Value of Early Postictal EEG in Children with Complex Febrile Seizures

et al. 2000

View full text Add to dashboard Cite

show abstract

“…13,14 There is a single study that found that a paroxysmal EEG was associated with a higher rate of afebrile seizures. 12 There is no evidence that interventions based on this test would alter outcome.…”

Section: Action Statementmentioning

confidence: 99%

Febrile Seizures: Guideline for the Neurodiagnostic Evaluation of the Child With a Simple Febrile Seizure

Seizures¹

2011

Pediatrics

388

190

View full text Add to dashboard Cite

OBJECTIVE:To formulate evidence-based recommendations for health care professionals about the diagnosis and evaluation of a simple febrile seizure in infants and young children 6 through 60 months of age and to revise the practice guideline published by the American Academy of Pediatrics (AAP) in 1996. METHODS:This review included search and analysis of the medical literature published since the last version of the guideline. Physicians with expertise and experience in the fields of neurology and epilepsy, pediatrics, epidemiology, and research methodologies constituted a subcommittee of the AAP Steering Committee on Quality Improvement and Management. The steering committee and other groups within the AAP and organizations outside the AAP reviewed the guideline. The subcommittee member who reviewed the literature for the 1996 AAP practice guidelines searched for articles published since the last guideline through 2009, supplemented by articles submitted by other committee members. Results from the literature search were provided to the subcommittee members for review. Interventions of direct interest included lumbar puncture, electroencephalography, blood studies, and neuroimaging. Multiple issues were raised and discussed iteratively until consensus was reached about recommendations. The strength of evidence supporting each recommendation and the strength of the recommendation were assessed by the committee member most experienced in informatics and epidemiology and graded according to AAP policy. CONCLUSIONS:Clinicians evaluating infants or young children after a simple febrile seizure should direct their attention toward identifying the cause of the child's fever. Meningitis should be considered in the differential diagnosis for any febrile child, and lumbar puncture should be performed if there are clinical signs or symptoms of concern. For any infant between 6 and 12 months of age who presents with a seizure and fever, a lumbar puncture is an option when the child is considered deficient in Haemophilus influenzae type b (Hib) or Streptococcus pneumoniae immunizations (ie, has not received scheduled immunizations as recommended), or when immunization status cannot be determined, because of an increased risk of bacterial meningitis. A lumbar puncture is an option for children who are pretreated with antibiotics. In general, a simple febrile seizure does not usually require further evaluation, specifically electroencephalography, blood studies, or neuroimaging.

show abstract

“…2,5,30,36 O achado de antecedente familiar positivo para CF em 19,2% das crianças corresponde aos valores inferiores relatados na literatura. 5,17,18,22 Observou-se no presente trabalho um grande incremento da ocorrência de AE da faixa etária de até 2 anos (2,6%) àquela com mais de 4 anos (32,3%). Certamente a influência da idade é importante para explicar o achado bastante variável de AE nos vários estudos.…”

Section: Discussão 1 Aspectos Clínicos E Eletrencefalográficosunclassified

Crise febril: correlação clínico-eletrencefalográfica em 1162 crianças

Fonseca

2007

J. epilepsy clin. neurophysiol.

View full text Add to dashboard Cite

RESUMOIntrodução: Crise febril (CF) é comum, e ocorre em aproximadamente 2 a 5% das crianças até 5 anos de idade. Objetivo e Métodos: Avaliar a relação entre aspectos clínicos e ocorrência de atividade epileptiforme (AE) no eletrencefalograma (EEG) em crianças com CF e, naquelas em que houve seguimento, observar, também, o aparecimento de crises epilépticas não febris (CNF). Resultados: Foram avaliadas 1162 crianças de 4 meses a 5 anos de idade. Houve predomínio de CF simples (82,4%) e de episódio único (62,0%). Houve maior recorrência de CF quando a primeira crise ocorreu antes dos 12 meses de idade ou quando era complexa. AE foi encontrada em porcentagem crescente com a idade da criança; em 3% dos pacientes até os dois anos de idade e 33% após os 4 anos. Pontas evocadas pela percussão de pés ou mãos (PE) ocorreu em 3,4% dos casos. CNF foi relatada em 38 (9,5%) crianças. Não houve correlação estatisticamente significativa entre o tipo e número de CF, idade de ocorrência da primeira CF, presença de AE e de PE no EEG e a ocorrência ou o tipo de CNF, no seguimento. Discussão: Há aspectos ainda controversos na literatura, como o prognóstico em relação ao desenvolvimento de epilepsia e o eventual efeito de AE persistente quanto à cognição e comportamento nas crianças que apresentam CF, a exigir pesquisas prospectivas longitudinais.Unitermos: crise febril, atividade epileptiforme, eletrencefalograma, crise não febril. ABSTRACT Febrile seizures: clinical-electroencephalographic correlation in 1162 childrenIntroduction: Febrile seizures (FS) occur in about 2-5% of the children from the age of 6 months do 5 years of age. Objective: The aim of this study is to analyze clinical and EEG aspects of children with febrile seizures. Methods: We retrospectively studied 1162 children (age range: 4 months to 5 years) with FS. The relationship between clinical and EEG abnormalities was statistically analyzed. Results: In the majority of cases there were simple febrile seizures (82%) and unique seizures (62%). The recurrence rate of FS was higher for children with the first seizure bellow 12 months of age, and when the FS were complicated. Ninetyfive (8.1%) children showed focal epileptiform activity (EA) in the first EEG, and 3.4% had somatosensory evoked spikes by foot or hand stimulation. There was a increase in percentage of EA with the increase of age (3% until 12 months and 33% after 48 moths). Afebrile seizures subsequent to the FS occurred in 9,4% of the cases. EA, a family history of seizures, and the type of FS were not significant risk factors for subsequent afebrile seizures. Discussion: In order to understand the relationship between FS and the occurrence of epilepsy, and to evaluate possible cognitive and behaviour problems associated to the persistent epileptiform activity there is a need of longitudinal studies.

show abstract

Longitudinal EEG and clinical study of children with febrile convulsions

Cited by 139 publications

References 20 publications

The Value of Early Postictal EEG in Children with Complex Febrile Seizures

The Value of Early Postictal EEG in Children with Complex Febrile Seizures

Febrile Seizures: Guideline for the Neurodiagnostic Evaluation of the Child With a Simple Febrile Seizure

Crise febril: correlação clínico-eletrencefalográfica em 1162 crianças

Contact Info

Product

Resources

About