Longitudinal evaluation of fluoride levels in nails of 18–30‐month‐old children that were using toothpastes with 500 and 1100 μg F/g

Amaral, Jackeline Gallo do; Freire, Isabelle Rodrigues; Valle-Neto, Eduardo F. R.; Cunha, Robson Frederico; Martinhon, Cleide Cristina Rodrigues; Delbem, Alberto Carlos Botazzo

doi:10.1111/cdoe.12103

Cited by 17 publications

(14 citation statements)

References 22 publications

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“…Studies of children in higher age groups in regions with temperate, subtropical, and tropical climates have observed a fluoride intake average below the results of this study [Rodrigues et al, 2009;Oganessian et al, 2011;Amaral et al, 2014]; in those case the cities had water with a fluoride concentration of 0.6-0.9 mg/l, being artificially or naturally fluoridated. With increasing age, the average fluoride intake tends to decrease due to the child's rising body weight and greater control over the expulsion of toothpaste remnants [Sohn et al, 2009].…”

Section: Discussioncontrasting

confidence: 83%

“…Fluoride data on the diets of children have been collected in regions of temperate and subtropical climates [Guha-Chowdhuryl et al, 1996;Rojas-Sanches et al, 1999;Cury, 2001, 2003;Paiva et al, 2003;Franco et al, 2005;Oganessian et al, 2011;Opydo-Szymaczek and Opydo, 2011;Amaral et al, 2014]. However, in tropical regions these data have been little explored [Omena et al, 2006;Rodrigues et al, 2009], wherein the first study only evaluated the fluoride intake from water and toothpaste, and the second study only had data on fluoride intake from diet.…”

confidence: 99%

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Total Fluoride Intake by Children from a Tropical Brazilian City

et al. 2015

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The main sources of fluoride intake by children are fluoridated water and toothpaste. Little has been studied regarding fluoride intake from these sources in regions with tropical climates and high temperatures throughout the year. This study aimed to determine the amount of fluoride ingested from diet and tooth brushing by children who live in a city with a tropical climate. Sixty-seven children from Teresina, Piauí, Brazil, took part in this study. The city's water supply was optimally fluoridated. The duplicate-diet method was used to determine the fluoride intake from diet. The intake of fluoride from dentifrice was determined by subtracting the amount of fluoride placed on the toothbrush and that recovered after brushing. The concentration of fluoride was measured using an ion-specific electrode and is expressed as milligrams/kilogram of body weight/day. The mean (±SD) total amount was 0.071 ± 0.036 mg F/kg body weight/day, and the relative contributions of diet and toothpaste were 0.025 ± 0.010 and 0.046 ± 0.035, respectively. The factors associated with fluoride intake from toothpaste were: use of children's toothpaste (p = 0.003), use of large amounts of toothpaste (p < 0.001), and a high frequency of tooth brushing (p = 0.003). Sixty-four percent of children had an intake of less than 0.07 mg F/kg body weight/day, which is considered the upper limit for an aesthetically tolerable fluorosis risk. The results suggest that the amount of fluoride ingested by most children who live in a Brazilian city with a tropical climate is considered safe in terms of the risk of dental fluorosis.

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Section: Discussioncontrasting

confidence: 83%

confidence: 99%

Total Fluoride Intake by Children from a Tropical Brazilian City

et al. 2015

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“…Concerns about excessive fluoride intake, particularly by children under 3 years of age, have prompted investigators to search for alternatives for the conventional formulations available. Besides achieving similar or superior anticaries effects when compared to the conventional dentifrice, both LFDs tested in the present study were also able to significantly reduce fluoride intake from the dentifrice during toothbrushing, as verified in a parallel study conducted with a subgroup of the children who were enrolled in the present research [31]. The systemic effect of this reduction was also observed in the resulting fluoride levels in fingerand toenails of the children [31], which are good indicators of fluoride absorption [32][33][34].…”

Section: Discussionsupporting

confidence: 74%

Anticaries effect of low-fluoride dentifrices with phosphates in children: A randomized, controlled trial

Freire

Pessan

Amaral

et al. 2016

Journal of Dentistry

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“…to organic or inorganic phosphate is significantly reduced when compared to 1,100 ppm F toothpaste [Amaral et al, 2014].…”

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confidence: 91%

Effectiveness of a Toothpaste with Low Fluoride Content Combined with Trimetaphosphate on Dental Biofilm and Enamel Demineralization in situ

et al. 2015

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Objective: The aim of the present study was to evaluate in situ whether a toothpaste with low fluoride associated with sodium trimetaphosphate (TMP) would provide similar effect to that of a 1,100 ppm F toothpaste. Design: This crossover double-blind study consisted of 4 phases (14 days each), during which 10 volunteers wore oral appliances containing 4 enamel bovine blocks. The cariogenic challenge was performed by the application of a 20% sucrose solution (6×/day). The toothpaste treatments (2×/day) were: placebo, 500 ppm F, 500 ppm F plus 1% TMP, and 1,100 ppm F. At the end, enamel mineral loss and biofilm composition were analyzed. Results: The toothpaste with 500 ppm F plus 1% TMP showed the lowest mineral loss (p < 0.05). Regarding the fluoride and calcium concentrations in the enamel and in the biofilm, there were no significant differences between 500 ppm F plus 1% TMP, and 1,100 ppm F toothpastes (p > 0.569), but they were significantly different when compared to toothpaste with 500 ppm F (p < 0.050). Conclusion: The addition of 1% TMP to a low-fluoride toothpaste reduces enamel demineralization in situ similar to a 1,100 ppm F toothpaste.

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Longitudinal evaluation of fluoride levels in nails of 18–30‐month‐old children that were using toothpastes with 500 and 1100 μg F/g

Abstract: The results of the longitudinal study suggest that the level of fluoride present in nails was lower with the use of toothpastes with a low fluoride concentration.

Cited by 17 publications

References 22 publications

Total Fluoride Intake by Children from a Tropical Brazilian City

Total Fluoride Intake by Children from a Tropical Brazilian City

Anticaries effect of low-fluoride dentifrices with phosphates in children: A randomized, controlled trial

Effectiveness of a Toothpaste with Low Fluoride Content Combined with Trimetaphosphate on Dental Biofilm and Enamel Demineralization in situ

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