Look what’s eroding through the chest wall? Salmonella osteomyelitis of the ribs in an immunocompetent adult not associated with sickle cell disease

Abstract

We describe a case of Salmonella typhimurium osteomyelitis in an immunocompetent adult male patient without sickle cell disease. We are not aware of a previous report of this combination.

Salmonella Osteomyelitis of the Rib Mimicking a Mammary Tumor: A Case Report

“…Salmonella osteomyelitis of the rib is extremely rare, with only five reported cases (Table 1) (Vartian 1997;Andrianopoulos et al 1998;Wilson et al 2005;Zheng et al 2009;Scarci et al 2010). This is the first case of salmonella osteomyelitis of the rib in an elderly woman.…”

“…In addition, culture tests of turbid pyogenic aspirate, blood, and tissues are useful for definitive diagnosis (Andrianopoulos et al 1998;Wilson et al 2005;Zheng et al 2009). In some reports, additional histopathological examination of excised tissues was performed for diagnosis (Wilson et al 2005;Scarci et al 2010).…”

“…Although no randomized or case-controlled studies for the treatment of salmonella osteomyelitis have been reported, and there is no consensus for antimicrobial guidelines and indications of surgery for treatment of infection ( Scarci et al 2010), drainage or resection of the affected rib portion and use of antibiotics have been previously described (Andrianopoulos et al 1998;Wilson et al 2005). In the current case, we performed curettage of the affected rib and soft tissue with antibiotic (levofloxacin) treatment after the surgery.…”

Chronic Salmonella Osteomyelitis in a Healthy, Immunocompetent Man

“…S almonella causes a variety of diseases, including gastroenteritis and typhoid fever 14,15 . Salmonella osteomyelitis is well known in individuals with hemoglobinopathies 2,4,16,21,22 and the immunocompromised 17,18 . When evaluating patients with sickle cell anemia, differentiation between vaso-occlusive pain and osteomyelitis may be difficult, but presenting signs and symptoms of Anteroposterior and lateral radiographs of the right knee from his second visit with sports medicine demonstrating a lytic lesion in the superomedial aspect of the distal femur with a surrounding border and associated effusion.…”

“…Salmonella causes a variety of diseases, including gastroenteritis and typhoid fever 14,15 . Salmonella osteomyelitis is well known in individuals with hemoglobinopathies 2,4,16,21,22 and the immunocompromised 17,18 . When evaluating patients with sickle cell anemia, differentiation between vaso-occlusive pain and osteomyelitis may be difficult, but presenting signs and symptoms of osteomyelitis include vague bone pain, difficulty ambulating, fever, elevated CRP and white cell count, and soft-tissue edema.…”