Lopinavir/r versus Nelfinavir as Salvage Therapy

Resino, Salvador; Álvaro-Meca, Alejandro; José, María Isabel de; Gurbindo, María Dolores; Ramos, José Tomás; Martín-Fontelos, Pablo; Muñoz‐Fernández, María Ángeles

doi:10.1097/01.inf.0000157922.19139.90

Pediatric Infectious Disease Journal

2005

DOI: 10.1097/01.inf.0000157922.19139.90

|View full text |Cite

Lopinavir/r versus Nelfinavir as Salvage Therapy

Salvador Resino

Alejandro Álvaro-Meca

María Isabel de José

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2005

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Nelfinavir

Perry¹,

Frampton²,

McCormack³

et al. 2005

Drugs

View full text Add to dashboard Cite

Nelfinavir (Viracept) is an orally administered protease inhibitor. In combination with other antiretroviral drugs (usually nucleoside reverse transcriptase inhibitors [NRTIs]), nelfinavir produces substantial and sustained reductions in viral load in patients with HIV infection. Nelfinavir may be used in the treatment of adults, adolescents and children aged >or=2 years with HIV infection. It can also be used in pregnancy. Resistance to nelfinavir may develop, but the most common mutation (D30N, appearing mainly in HIV-1 subtype B) does not confer resistance to other protease inhibitors, thereby conserving these agents for later use. Although less effective than lopinavir/ritonavir, the preferred first-line treatment in US guidelines, nelfinavir is positioned as an alternative agent for the treatment of adults and adolescents with HIV infection and is an option for those unable to tolerate other protease inhibitors. Nelfinavir also has a role in the management of pregnant patients as well as paediatric patients with HIV infection.

show abstract

Nelfinavir

Perry¹,

Frampton²,

McCormack³

et al. 2005

Drugs

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Lopinavir/r versus Nelfinavir as Salvage Therapy

Cited by 1 publication

References 5 publications

Nelfinavir

Nelfinavir

Contact Info

Product

Resources

About