Low ankle–brachial index is a predictive factor for initial severity of acute ischaemic stroke

Lee, D. H.; Kim, J.; Lee, H.; Cha, Myoung-Jin; Kim, Y. D.; Nam, Hyo Suk; Nam, Chung Mo; Heo, Ji Hoe

doi:10.1111/j.1468-1331.2011.03652.x

Cited by 23 publications

(28 citation statements)

References 35 publications

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“…According to several studies, older age, lower BMI, diabetes mellitus, atrial fibrillation and the NIHSS score at admission are significantly associated with PAD among Asian patients with AIS, which is consistent with the present results . Subclinical or clinical leg dysfunction with PAD might play a role in the initial stroke severity estimated using the NIHSS score in patients with a low ABI .…”

Section: Discussionsupporting

confidence: 91%

“…However, the prevalence of low ABI values (24.2%) in the present study was relatively higher than that previously reported in patients of Asian ethnicity regardless of the effect of atrial fibrillation. In general, Asian patients have a lower prevalence of low ABI values (7–18%) than white patients (20–30%) . The main explanation for the differences in the prevalence of PAD among patients with AIS between the present study and other Asian studies might be the age of the patients.…”

Section: Discussioncontrasting

confidence: 50%

“…(1147 patients, mean age 64.5 years, prevalence of a low ABI 7.4%) and Ratanakorn et al . (747 patients, mean age 63.5 years, prevalence of a low ABI 18.1%) …”

Section: Discussionmentioning

confidence: 99%

“…The ankle‐brachial index (ABI) has been used as a diagnostic criterion for peripheral arterial disease (PAD). Patients with AIS presenting with PAD also have an increased cardiovascular risk and a worse prognosis . An ABI <0.9 is a clear predictor of a poor functional outcome and subsequent cardiovascular risk in patients with AIS …”

Section: Introductionmentioning

confidence: 99%

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Increased blood pressure variability during the subacute phase in patients with ischemic stroke presenting with a low ankle‐brachial index

Naito

Hosomi

Kuzume

et al. 2020

Geriatrics Gerontology Int

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Aim: This study aimed to evaluate the associations of blood pressure (BP) variability in patients with ischemic stroke during the subacute phase using ambulatory blood pressure monitoring and the ankle-brachial index (ABI). Methods:We retrospectively examined 831 consecutive patients (women 44.8%, mean age 76 AE 12 years) with acute ischemic stroke who underwent 24-h ambulatory blood pressure monitoring during the subacute phase of stroke (median 9 days from onset) and an ABI examination. BP variability was evaluated by assessing the standard deviation and coefficient of variation of systolic BP and diastolic BP. A low ABI was defined as an ABI <0.9.Results: Of the 831 patients, 201 (24.2%) had a low ABI. Older age, lower body mass index, diabetes mellitus, chronic kidney disease, atrial fibrillation and a higher National Institutes of Health Stroke Scale score at admission were independently associated with a low ABI. The patients with a low ABI had a higher mean 24-h diastolic BP, higher standard deviation of both BP measurements (systolic BP and diastolic BP) and a higher coefficient of variation in both BP measurements than those with a higher ABI. According to the multivariable linear regression analysis, a low ABI was independently associated with increased BP variability (a high standard deviation or coefficient of variation of both BP measurements) after adjusting for baseline confounders. Conclusions:A low ABI was associated with increased BP variability during the subacute ischemic phase. Geriatr Gerontol Int 2020; 20: 448-454.

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Section: Discussionsupporting

confidence: 91%

Section: Discussioncontrasting

confidence: 50%

“…(1147 patients, mean age 64.5 years, prevalence of a low ABI 7.4%) and Ratanakorn et al . (747 patients, mean age 63.5 years, prevalence of a low ABI 18.1%) …”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Increased blood pressure variability during the subacute phase in patients with ischemic stroke presenting with a low ankle‐brachial index

Naito

Hosomi

Kuzume

et al. 2020

Geriatrics Gerontology Int

View full text Add to dashboard Cite

show abstract

“…Low ABI is commonly defined as ABI <0.9 and provides good sensitivity (80%) and excellent specificity (95%) to detect PAD [4]. ABI is also associated with poor initial stroke severity [21] and predicts poor prognosis and mortality in patients with stroke [2]. However, several previous studies have shown that low ABI was not sensitive enough to detect asymptomatic PAD in the general population [22].…”

Section: Discussionmentioning

confidence: 99%

Predicting Stroke Outcomes Using Ankle-Brachial Index and Inter-Ankle Blood Pressure Difference

Han

Choi

et al. 2020

JCM

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Background: This study investigated the association of high ankle-brachial index difference (ABID) and systolic inter-ankle blood pressure difference (IAND) with short-and long-term outcomes in acute ischemic stroke patients without peripheral artery disease (PAD). Methods: Consecutive patients with acute ischemic stroke who underwent ankle-brachial index (ABI) measurement were enrolled. ABID was calculated as |right ABI-left ABI|. IAND and systolic inter-arm blood pressure difference (IAD) were calculated as |right systolic blood pressure -left systolic blood pressure|. Poor functional outcome was defined as modified Rankin Scale score ≥3 at 3 months. Major adverse cardiovascular events (MACEs) were defined as stroke recurrence, myocardial infarction, or death. Results: A total of 2901 patients were enrolled and followed up for a median of 3.1 (interquartile range, 1.6-4.7) years. Among them, 2643 (84.9%) patients did not have PAD. In the logistic regression analysis, ABID ≥ 0.15 and IAND ≥ 15 mmHg were independently associated with poor functional outcome (odds ratio (OR), 1.970, 95% confidence interval (CI), 1.175-3.302; OR, 1.665, 95% CI, 1.188-2.334, respectively). In Cox regression analysis, ABID ≥0.15 and IAND ≥ 15 mmHg were independently associated with MACEs (hazard ratio (HR), 1.514, 95% CI, 1.058-2.166; HR, 1.343, 95% CI, 1.051-1.716, respectively) and all-cause mortality (HR, 1.524, 95% CI, 1.039-2.235; HR, 1.516, 95% CI, 1.164-1.973, respectively) in patients without PAD. Conclusion: High ABID and IAND are associated with poor short-term outcomes, long-term MACE occurrence, and all-cause mortality in acute ischemic stroke without PAD.

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Polyvascular Disease: Definition, Epidemiology, Relevance

Aboyans

2015

PanVascular Medicine

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Low ankle–brachial index is a predictive factor for initial severity of acute ischaemic stroke

Cited by 23 publications

References 35 publications

Increased blood pressure variability during the subacute phase in patients with ischemic stroke presenting with a low ankle‐brachial index

Increased blood pressure variability during the subacute phase in patients with ischemic stroke presenting with a low ankle‐brachial index

Predicting Stroke Outcomes Using Ankle-Brachial Index and Inter-Ankle Blood Pressure Difference

Polyvascular Disease: Definition, Epidemiology, Relevance

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