Low dose of Hyaluronidase to treat over correction by HA filler–A Case Report.

Menon, Harikumar; Thomas, Mohan; D’silva, James

doi:10.1016/j.bjps.2010.01.005

Cited by 34 publications

(12 citation statements)

References 5 publications

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“…The only treatment for overcorrection is to use hyalase to breakdown the filler. [21] In an effort to standardise the technique of dermal filling we introduced the PPT method (PPT technique) which uses a minimum amount of filler in a systematic method to optimise results.…”

Section: Discussionmentioning

confidence: 99%

Anatomic and mechanical considerations in restoring volume of the face with use of hyaluronic acid fillers with a novel layered technique

Thomas¹,

D’silva²,

Borole³

et al. 2014

Indian J Plast Surg

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Context:Facial fillers have revolutionized the field of cosmetic facial rejuvenation as it has become the prime sought – after rejuvenation procedure offering youthful, 3-dimensional look with minimal invasiveness. Fillers are expensive and need to be redone periodically hence a sound understanding of structural basis on which they are laid is important in reducing the quantity of filler required in each sitting as well as increasing the longevity of results.Aim:The aim of the following study is to analyse a novel method of facial filling “The pillars pyramids and tie beams (PPT)” technique and its advantages over the conventional methods.Subjects and Methods:A novel technique of injecting the facial fillers was employed on 67 patients visiting our clinic. These patients were followed-up for a period of 3 years.Results:We observed that the amount of filler material required in initial sitting remains the same, however the frequency of touch up visits is decreased and so is the amount of filler material required for follow-up injections.Conclusion:Facial contour remodelling is being revolutionised by the new filler materials for volume augmentation and no uniform consensus has been reached on the techniques currently used in clinical practice. We advocate this novel PPT technique of facial filling in facial rejuvenation to restore a youthful look as a primary goal.

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Section: Discussionmentioning

confidence: 99%

Anatomic and mechanical considerations in restoring volume of the face with use of hyaluronic acid fillers with a novel layered technique

Thomas¹,

D’silva²,

Borole³

et al. 2014

Indian J Plast Surg

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show abstract

“…It is also the author's and others' experience that overfills, superficial implantation, and inflammatory reactions by Restylane can be rapidly corrected by 1.5 to 150 units of the hyaluronidase ( Figure 1A-D). [6][7][8][9]20,[58][59][60] For more resistant gels, higher doses or repetitive injections of the enzyme are required. 7, 58 Jones and colleagues 53 suggested a rule of thumb: for each 0.1 mL of HA to be eradicated in vivo, the clinician should begin with 5 units of hyaluronidase for Restylane and 10 units for Juvederm.…”

Section: Are Different Doses Of Hyaluronidase Needed To Treat Differementioning

confidence: 99%

Hyaluronidase Caveats in Treating Filler Complications

Landau

2015

Dermatologic Surgery

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“…In areas of thinner skin, such as the inferior eyelids, lower doses of hyaluronidase have been successfully employed. Menon et al reported the case of a patient who received 0.4 mL of HA in the lower lids and developed blue discoloration and evidence of overcorrection [11]. The patient was initially treated with 3 units (0.2 mL injected volume) of hyaluronidase reconstituted in normal saline into the affect regions.…”

Section: Periorbital Lesionsmentioning

confidence: 99%

“…For example, the doses of hyaluronidase reported in the literature to reverse HA filler injection vary greatly from 5 to 300 units [5,7,11].…”

Section: Introductionmentioning

confidence: 99%

The Use of Hyaluronidase in Cosmetic Dermatology: A Review of the Literature

2015

J Clin Investig Dermatol

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Background: Hyaluronidase can be employed to manage a variety of complications associated with cosmetic hyaluronic acid (HA) filler injection. However, the indications and treatment protocol for hyaluronidase use have not been well established.Objective: Review of the available literature to describe the use of hyaluronidase in the reversal of HA filler injection.Methods: PubMed/MEDLINE databases were utilized to identify case reports and studies pertaining to the use of hyaluronidase after HA filler injection.Results: Hyaluronidase can be successfully employed in the management of uncomplicated nodules and overcorrection, inflamed nodules, or tissue ischemia associated with HA filler injection. Hyaluronidase use is dependent on the clinical indication, anatomical location, and original injected HA quantity. Conclusion:Hyaluronidase is an important tool for clinicians utilizing cosmetic HA filler injection. Further reports and studies are warranted to firmly establish the ideal treatment protocol.

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Low dose of Hyaluronidase to treat over correction by HA filler–A Case Report.

Cited by 34 publications

References 5 publications

Anatomic and mechanical considerations in restoring volume of the face with use of hyaluronic acid fillers with a novel layered technique

Anatomic and mechanical considerations in restoring volume of the face with use of hyaluronic acid fillers with a novel layered technique

Hyaluronidase Caveats in Treating Filler Complications

The Use of Hyaluronidase in Cosmetic Dermatology: A Review of the Literature

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