Low-Dose Radiation Advances in Coronary Computed Tomography Angiography in the Diagnosis of Coronary Artery Disease

Richards, Caryl E; Obaid, Daniel R.

doi:10.2174/1573403x15666190222163737

Cited by 28 publications

(12 citation statements)

References 98 publications

(128 reference statements)

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“…C | Comparison on effective radiation dose of CT scanningRadiation damage of CCTA was considered since the study report published by Redberg et al20 How to keep a balance of reducing effective radiation dose and maintaining image quality of coronary CT scanning is a hot research topic at present 21. In our study, the effective radiation dose of both heart rate of HR < 70/min and 70 ≤ HR ≤ 90/min when using prospective ECG-gated method on 2nd generation (128-slice) row dual source CT (Siemens) is lower than the same method on 320 row CT (Toshiba).…”

mentioning

confidence: 99%

Comparison on radiation effective dose and image quality of right coronary artery on prospective ECG‐gated method between 320 row CT and 2nd generation (128‐slice) dual source CT

Hou

Huang

et al. 2020

J Applied Clin Med Phys

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This retrospective study was to compare the image quality of right coronary artery (RCA) and effective radiation dose on prospective ECG-gated method between 320 row computed tomography (CT) and 2nd generation (128-slice) dual source CT. A total of 215 candidates underwent CT coronary angiography using prospective ECG-gated method, 120 patients enrolled in 320 row CT group, and 95 patients in dual source CT group. We divided RCA image quality scores as 1/2/3/4, which means excellent/good/adequate/not assessable and heart rates were considered, as well as the radiation dose. There is no statistically significant difference of RCA image quality of Score 1/2 between 320 row CT and 2nd generation dual source CT, but lower heart rate (<70/min) improved RCA image quality. Meanwhile, the 2nd generation dual source CT scan have significant lower radiation dose. For patients with high level heart rate variation, both prospective ECG-gated method of 320 row CT scan (Toshiba) and 2nd generation dual source CT scan (Siemens) basically provided good image quality on RCA. There is an advantage of effective radiation dose reduction in prospective ECG-gated method using the 2nd generation dual source CT scan. After the iodine contrast agent was injected into elbow vein, the threshold triggering method was used to carry out prospective gated scanning, and the acquired fault image was reconstructed by the standard post-processing software of each manufacturer. The radiation dose value is obtained through the dose report automatically generated after each scan.

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confidence: 99%

Comparison on radiation effective dose and image quality of right coronary artery on prospective ECG‐gated method between 320 row CT and 2nd generation (128‐slice) dual source CT

Hou

Huang

et al. 2020

J Applied Clin Med Phys

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“…With the rapid development of computed tomography (CT), coronary CT angiography (CCTA) has been widely used in the diagnosis of coronary heart disease [16,17] . However, the higher radiation dose from the CCTA examination is a concern of radiologists [18,19] .…”

Section: Discussionmentioning

confidence: 99%

Comparison of image quality and radiation dose using different pre-ASiR-V and post-ASiR-V levels in coronary computed tomography angiography

Zhao¹,

Li²,

Geng³

et al. 2020

Preprint

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Objective: To characterize the optimal pre-(ASiR-V and post-ASiR-V for improving image quality and reducing the radiation dose in CCTA. Methods: The study was divided into two parts. In part I, 150 patients for CCTA were prospectively enrolled and randomly divided into five groups (A, B, C, D, and E), with progressive scanning from 40% to 80% pre-ASiR-V with 10% intervals and reconstructing with 70% post-ASiR-V. The SNR and CNR were calculated. Subjective image quality was assessed using a five-point scale. The radiation dose was recorded and calculated after statistical analysis by optimizing for the best pre-ASiR-V value with the lowest radiation dose while maintaining overall image quality. In part II, the images were reconstructed with the recommended optimal pre-ASiR-V values in part I (D group) was divided into six subgroups (D0-D5 with 40%-90% post-ASiR-V and interval 10%, respectively.).The SNR and CNR of D0-D5 subgroups were calculated and analyzed using one-way analysis of variance, and the consistency of the subjective scores used the k test. Results: There was no significant difference in the SNRs, CNRs, and image quality scores among A, B, C, and D groups. The SNR, CNR, and image quality scores of the E group were lower than those of the A, B, C, and D groups. The mean EDs in the B, C, and D groups were reduced by 7.01%, 13.37%, and 18.87%, respectively, when compared with that of the A group. The SNR and CNR of the D4-D5 subgroups were higher than the D0-D3 subgroups, and the image quality scores of the D4 subgroups were higher than the other subgroups. Conclusion: The wide-detector combined with 70% pre-ASiR-V and 80% post-ASiR-V significantly reduced the radiation dose of CCTA while maintaining overall image quality compared with the manufacture's recommendation.

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“… ⁎⁎ Quality CCTA images with ~ 1 mSv radiation exposure can sometimes be obtained in younger patients without overweight/obesity, or when utilizing low-dose CCTA protocols. [ 42 , 43 , 53 ] CMR = Cardiac magnetic resonance, CT = computerized tomography, DXA = Dual x-ray absorptiometry, FFR = Fractional flow reserve, IVUS = Intravascular ultrasound, MRI = Magnetic resonance imaging, MRI-PDFF = MRI proton density fat fraction, MRS = Magnetic resonance spectroscopy, MUGA = Multiple-gated acquisition scan, OCT = Optical coherence tomography, PET = Positron emission tomography, SPECT = Single-photon emission computerized tomography, VCTE = Vibration-controlled transient elastography. Appropriate use of imaging studies includes procedures most likely to provide safe and definitive answers to the diagnostic questions raised, and least likely to prompt further imaging studies and invasive downstream procedures, irrespective of the initial imaging study results.…”

Section: Appropriate Use [ 4 5 ]mentioning

confidence: 99%

“…Quality CCTA images with ~ 1 mSv radiation exposure can sometimes be obtained in younger patients without overweight/obesity, or when utilizing low-dose CCTA protocols. [ 42 , 43 , 53 ]…”

Section: Appropriate Use [ 4 5 ]mentioning

confidence: 99%

Ten things to know about ten imaging studies: A preventive cardiology perspective (“ASPC top ten imaging”)

Bays

Khera

Blaha³

et al. 2021

American Journal of Preventive Cardiology

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Knowing the patient's current cardiovascular disease (CVD) status, as well as the patient's current and future CVD risk, helps the clinician make more informed patient-centered management recommendations towards the goal of preventing future CVD events. Imaging tests that can assist the clinician with the diagnosis and prognosis of CVD include imaging studies of the heart and vascular system, as well as imaging studies of other body organs applicable to CVD risk. The American Society for Preventive Cardiology (ASPC) has published “Ten Things to Know About Ten Cardiovascular Disease Risk Factors.” Similarly, this “ASPC Top Ten Imaging” summarizes ten things to know about ten imaging studies related to assessing CVD and CVD risk, listed in tabular form. The ten imaging studies herein include: (1) coronary artery calcium imaging (CAC), (2) coronary computed tomography angiography (CCTA), (3) cardiac ultrasound (echocardiography), (4) nuclear myocardial perfusion imaging (MPI), (5) cardiac magnetic resonance (CMR), (6) cardiac catheterization [with or without intravascular ultrasound (IVUS) or coronary optical coherence tomography (OCT)], (7) dual x-ray absorptiometry (DXA) body composition, (8) hepatic imaging [ultrasound of liver, vibration-controlled transient elastography (VCTE), CT, MRI proton density fat fraction (PDFF), magnetic resonance spectroscopy (MRS)], (9) peripheral artery / endothelial function imaging (e.g., carotid ultrasound, peripheral doppler imaging, ultrasound flow-mediated dilation, other tests of endothelial function and peripheral vascular imaging) and (10) images of other body organs applicable to preventive cardiology (brain, kidney, ovary). Many cardiologists perform cardiovascular-related imaging. Many non-cardiologists perform applicable non-cardiovascular imaging. Cardiologists and non-cardiologists alike may benefit from a working knowledge of imaging studies applicable to the diagnosis and prognosis of CVD and CVD risk – both important in preventive cardiology.

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Low-Dose Radiation Advances in Coronary Computed Tomography Angiography in the Diagnosis of Coronary Artery Disease

Cited by 28 publications

References 98 publications

Comparison on radiation effective dose and image quality of right coronary artery on prospective ECG‐gated method between 320 row CT and 2nd generation (128‐slice) dual source CT

Comparison on radiation effective dose and image quality of right coronary artery on prospective ECG‐gated method between 320 row CT and 2nd generation (128‐slice) dual source CT

Comparison of image quality and radiation dose using different pre-ASiR-V and post-ASiR-V levels in coronary computed tomography angiography

Ten things to know about ten imaging studies: A preventive cardiology perspective (“ASPC top ten imaging”)

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