Low-fouling electrospun PLLA films modified with zwitterionic poly(sulfobetaine methacrylate)-catechol conjugates

Yang, Wenjing; Sundaram, Harihara S.; Ella, Jean-Rene; He, Nongyue; Jiang, Shaoyi

doi:10.1016/j.actbio.2016.05.035

Cited by 46 publications

(38 citation statements)

References 57 publications

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“…Modification of the PLLA surface is commonly used to modulate the affinity of this polymer with the cells [38,39,40,41,42]. Many different functional groups, including diethylenetriamine, 2-(2-aminoethoxy)ethanol or GRGDS (cell adhesion peptide) [40], aldehyde and amine groups [41], and poly(sulfobetaine methacrylate)-catechol conjugates [42] have been used to improve stem cells adhesion and proliferation on PLLA polymer (both fibrous and film forms).…”

Section: Discussionmentioning

confidence: 99%

Surface Hydrophilicity of Poly(l-Lactide) Acid Polymer Film Changes the Human Adult Adipose Stem Cell Architecture

et al. 2018

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Current knowledge indicates that the molecular cross-talk between stem cells and biomaterials guides the stem cells' fate within a tissue engineering system. In this work, we have explored the effects of the interaction between the poly(L-lactide) acid (PLLA) polymer film and human adult adipose stem cells (hASCs), focusing on the events correlating the materials' surface characteristics and the cells' plasma membrane. hASCs were seeded on films of pristine PLLA polymer and on a PLLA surface modified by the radiofrequency plasma method under oxygen flow (PLLA+O 2 ). Comparative experiments were performed using human bone-marrow mesenchymal stem cells (hBM-MSCs) and human umbilical matrix stem cells (hUCMSCs). After treatment with oxygen-plasma, the surface of PLLA films became hydrophilic, whereas the bulk properties were not affected. hASCs cultured on pristine PLLA polymer films acquired a spheroid conformation. On the contrary, hASCs seeded on PLLA+O 2 film surface maintained the fibroblast-like morphology typically observed on tissue culture polystyrene. This suggests that the surface hydrophilicity is involved in the acquisition of the spheroid conformation. Noteworthy, the oxygen treatment had no effects on hBM-MSC and hUCMSC cultures and both stem cells maintained the same shape observed on PLLA films. This different behavior suggests that the biomaterial-interaction is stem cell specific.

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Section: Discussionmentioning

confidence: 99%

Surface Hydrophilicity of Poly(l-Lactide) Acid Polymer Film Changes the Human Adult Adipose Stem Cell Architecture

et al. 2018

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“…Catechol‐functionalized zwitterionic polymers such as poly(carboxybetaine), poly(carboxybetaine methacrylate) [Fig. (D)], and poly(sulfobetaine methacrylate) (pSBMA) have been reported in the literature.…”

Section: Biomedical Applications Of Biomimetic Polymer Adhesivesmentioning

confidence: 99%

Recent approaches in designing bioadhesive materials inspired by mussel adhesive protein

Forooshani

Lee

2016

J. Polym. Sci. Part A: Polym. Chem.

534

464

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Marine mussels secret protein‐based adhesives, which enable them to anchor to various surfaces in a saline, intertidal zone. Mussel foot proteins (Mfps) contain a large abundance of a unique, catecholic amino acid, Dopa, in their protein sequences. Catechol offers robust and durable adhesion to various substrate surfaces and contributes to the curing of the adhesive plaques. In this article, we review the unique features and the key functionalities of Mfps, catechol chemistry, and strategies for preparing catechol‐functionalized polymers. Specifically, we reviewed recent findings on the contributions of various features of Mfps on interfacial binding, which include coacervate formation, surface drying properties, control of the oxidation state of catechol, among other features. We also summarized recent developments in designing advanced biomimetic materials including coacervate‐forming adhesives, mechanically improved nano‐ and micro‐composite adhesive hydrogels, as well as smart and self‐healing materials. Finally, we review the applications of catechol‐functionalized materials for the use as biomedical adhesives, therapeutic applications, and antifouling coatings. © 2016 The Authors. Journal of Polymer Science Part A: Polymer Chemistry Published by Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2017, 55, 9–33

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“…Inspired by biosystems, which transmit signals through long‐distance ion transportation, ionic hydrogels have emerged as promising materials for strain sensors 6,7 . Zwitterionic polymers, due to their excellent hydration ability induced by hydrogen bonding and electrostatic interactions, always have been intensively used as a new class of antifouling materials 8,9 . Recently, the applications of zwitterions in wearable devices have been developed.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of alginate‐P(SBMA‐co‐AAm) hydrogels with ultrastretchability, strain sensitivity, self‐adhesiveness, biocompatibility, and self‐cleaning function for strain sensors

Jin

Jiang

Qiao

et al. 2020

J of Applied Polymer Sci

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Conductive hydrogels have attracted a myriad of interest due to their potential applications for human motion monitoring, personal healthcare diagnosis and so forth. However, fabrication of hydrogel-based strain sensors integrating with ultrastretchability, adhesiveness, strain sensitivity, biocompatibility, and self-cleaning function is still a challenge. Herein, a new type of semiinterpenetrating multifunctional hydrogels, which integrated all above practical features magically were prepared via a facile one-pot in-situ radical copolymerization method. Thereinto, [2-(methacryloyloxy) ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide (SBMA) and acrylamide (AAm) copolymers cross-linked by N,N 0-Methylenebisacrylamide (MBAA) served as the soft and functional matrix, whereas alginate was employed as the enhanced component. The transparent zwitterionic hydrogels had a max elongation and ionic conductivity of 1353% and 0.15 S/m, respectively. They could adhere onto various surfaces, including steel, glass, skin, and rubber. The repeatable adhesiveness, linear strain sensitivity within 0%-250% tensile strain and 0%-30% compressive strain provided remarkable working range and using stability. What's more notable was that the biocompatibility and self-cleaning function tested by MTT, live/ dead assay, allergy patch tests, and plate colony-counting method imparted great possibility of practical application for strain sensors to hydrogels from a biological point of view.

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Low-fouling electrospun PLLA films modified with zwitterionic poly(sulfobetaine methacrylate)-catechol conjugates

Cited by 46 publications

References 57 publications

Surface Hydrophilicity of Poly(l-Lactide) Acid Polymer Film Changes the Human Adult Adipose Stem Cell Architecture

Surface Hydrophilicity of Poly(l-Lactide) Acid Polymer Film Changes the Human Adult Adipose Stem Cell Architecture

Recent approaches in designing bioadhesive materials inspired by mussel adhesive protein

Fabrication of alginate‐P(SBMA‐co‐AAm) hydrogels with ultrastretchability, strain sensitivity, self‐adhesiveness, biocompatibility, and self‐cleaning function for strain sensors

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