Low frequency of clinically silent circulating emboli in patients with mitral valve prolapse or patent foramen ovale detected by bigated transcranial Doppler ultrasound

Dw, Droste; Schlossberg, R; Mitüsch, Rolf; Kaps, Manfred

doi:10.1080/01616412.1998.11740554

Cited by 11 publications

(4 citation statements)

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“…37 The absence of MES in patients with mitral valve prolapse and the low frequency of MES in patients with patent foramen ovale (PFO) reflect the reduced embolic potential of these two cardiac abnormalities. 41 Transcranial Doppler monitoring after the intravenous injection of agitated saline reliably detects paradoxical cerebral embolism through a PFO. 42 …”

Section: Cardiac Disordersmentioning

confidence: 99%

Clinical application of transcranial Doppler monitoring for embolic signals

Azarpazhooh

Chambers

2006

Journal of Clinical Neuroscience

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Section: Cardiac Disordersmentioning

confidence: 99%

Clinical application of transcranial Doppler monitoring for embolic signals

Azarpazhooh

Chambers

2006

Journal of Clinical Neuroscience

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“…5 In vivo, cerebral ischemia has been postulated as one of several potential triggers for migraine attacks. 7 Most of these microembolic signals are thought to arise from thrombi of the venous circulation. 7 Most of these microembolic signals are thought to arise from thrombi of the venous circulation.…”

mentioning

confidence: 99%

Percutaneous closure of patent foramen ovale reduces the frequency of migraine attacks

Schwerzmann¹,

Wiher²,

Nedeltchev³

et al. 2004

Neurology

249

165

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Among 215 patients referred for percutaneous closure of patent foramen ovale (PFO) after presumed paradoxical embolism, we assessed the prevalence of migraine. In the year prior to PFO closure, 48 (22%) patients had migraine, twice the expected prevalence of 10 to 12% in the general European population. In patients with migraine with aura, percutaneous PFO closure reduced the frequency of migraine attacks by 54% (1.2 +/- 0.8 vs 0.6 +/- 0.8 per month; p = 0.001) and in patients with migraine without aura by 62% (1.2 +/- 0.7 vs 0.4 +/- 0.4 per month; p = 0.006). PFO closure did not have an effect on headache frequency in patients with nonmigraine headaches (1.4 +/- 0.9 vs 1.0 +/- 0.9 per month; p = NS).

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“…Droste et al documented MES in three out of 14 cases, whereas other investigators detected MES in 27% of PFO positive patients and 18% of PFO negative patients (OR = 1.76, P = .327). 108,109 In addition, the mean number of MES per hour was higher in PFO cases (.70 ± 1.47 vs. .23 ± .55; P = .026). Moreover, when PFO was combined with atrial septal aneurysm, MES counts were significantly higher than in all other patient groups.…”

Section: Patent Foramen Ovalementioning

confidence: 91%

“…A limited number of studies have assessed MES presence in individuals with PFO. Droste et al documented MES in three out of 14 cases, whereas other investigators detected MES in 27% of PFO positive patients and 18% of PFO negative patients (OR = 1.76, P = .327) . In addition, the mean number of MES per hour was higher in PFO cases (.70 ± 1.47 vs. .23 ± .55; P = .026).…”

Section: Cardiac Sourcesmentioning

confidence: 93%

The Role of Transcranial Doppler Monitoring in Patients with Multi‐Territory Acute Embolic Strokes: A Review

Kargiotis

Psychogios

Safouris

et al. 2019

Journal of Neuroimaging

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Acute multi‐territory, embolic cerebral infarctions are often associated with serious underlying clinical conditions including the presence of highly “active” emboligenic sources causing that in turn may result in high early recurrence rates. Prompt diagnosis, risk stratification, and treatment are substantial for the prevention of subsequent embolization that would result in further clinical deterioration. Among other clinical investigations, transcranial Doppler (TCD) monitoring is highly efficacious for the detection of microembolic signals (MES) that correspond to microthrombi entering the intracranial circulation. The presence and burden of MES, especially in multiple intracranial arteries, is clearly associated with an increased risk of symptomatic, recurrent embolization, and thus can justify a more aggressive treatment approach (clopidogrel load followed by dual antiplatelet therapy or alternatively therapeutic dose of low‐molecular‐weight heparin). In this narrative review, we discuss the most important causes of multi‐territory embolic ischemic strokes and also underscore the utility of TCD as a noninvasive tool for the diagnosis, risk stratification, and treatment.

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Low frequency of clinically silent circulating emboli in patients with mitral valve prolapse or patent foramen ovale detected by bigated transcranial Doppler ultrasound

Cited by 11 publications

References 0 publications

Clinical application of transcranial Doppler monitoring for embolic signals

Clinical application of transcranial Doppler monitoring for embolic signals

Percutaneous closure of patent foramen ovale reduces the frequency of migraine attacks

The Role of Transcranial Doppler Monitoring in Patients with Multi‐Territory Acute Embolic Strokes: A Review

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