A B S T R A C T Studies were conducted during the 2013 and 2014 cropping seasons at the University for Development Studies, Nyankpala, Ghana to determine leaf area indices of three Sorghum (Sorghum bicolor (L.) Moench) varieties using the graphical approach. Three varieties viz., Kapala, Kadaga and Dorado were planted and applied with three rates: 0-0-0, 45-30-30, 35-20-20 and 45:30:30 of N, P and K, respectively. Treatment combinations were replicated three times in RCBD. Results indicated that the application of N, P and K at 45:30:30 or 35-20-20 to variety Dorado or Kadaga significantly increased leaf number, seed weight, grain yield and LAI of Sorghum. The data also showed that LAI correlated positively with panicle length and number of leaves. The relationships between LAI and 100 seed weight and LAI and grain yield were also high but negative. The leaf area constants for Sorghum have been developed and were found to be 0.723, 0.661 and 0.545, respectively, for varieties Kadaga, Kapala and Dorado. They can be used by researchers in computing LAI to predict growth and development of Sorghum. Farmers in the study area who cultivate Dorado or Kadaga should apply N, P and K at 45:30:30 to increase growth and yield of Sorghum.