Based on the electromagnetically induced transparency (EIT) model and the higher-order Poincaré sphere (HOPS) framework, we establish a general paradigm to investigate the paraxial evolution of a vector beam in a tripod EIT system. By quantum-optical analogy, we introduce a formalism with a generalized Pauli-like equation under rotational invariance, in which the pseudo-spin-orbit coupling (PSOC) and the spin-orbit nonseparability of light can coexist. More importantly, we find that both the PSOC-based real and imaginary potentials play a key role in controlling and modulating the nonseparable state of the vector beam to traverse the entire HOPS, where the orientation and ellipticity of the transmitted polarization can be modified by varying the PSOC coefficients. Therefore, an all-optical scheme can be proposed to improve the flexibility for tailoring the space-variant polarization of light in coherent media, where the tunable spatial-polarization multiplexing may be useful in conventional and quantum information processing.