Low-Noise Integrated Potentiostat for Affinity-Free Protein Detection With 12 nV/rt-Hz at 30 Hz and 1.8 pA<sup>rms</sup>Resolution

Fischer, Sean R.; Muratore, Dante Gabriel; Weinreich, Stephen; Pena-Perez, Aldo; Walker, Ross M.; Gupta, Chaitanya; Howe, Roger T.; Murmann, Boris

doi:10.1109/lssc.2019.2926644

Cited by 5 publications

(2 citation statements)

References 13 publications

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“…The continuous miniaturization of integrated electronic circuits led to the design of a single-chip potentiostat that greatly increased the miniaturization of electrochemical sensors. 136 4.2.1 Cations. A highly selective sensor for Ag + was developed by preparing a membrane containing TPFCorrH 3 as the electroactive component, 2-nitrophenyl octyl ether (o-NPOE) as a plasticizer and the additive sodium tetraphenylborate (NaTPB).…”

Section: Electrochemical Sensorsmentioning

confidence: 99%

Corroles at work: a small macrocycle for great applications

2022

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Section: Electrochemical Sensorsmentioning

confidence: 99%

Corroles at work: a small macrocycle for great applications

2022

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“…Moreover, the 1/f noise components generated in M 1 and M 2 act as the main noise contributors. Therefore, designing a current mirror with low-noise [12,13] and mismatch-tolerant characteristics is critical [14,15].…”

Section: Introductionmentioning

confidence: 99%

A Potentiostat Readout Circuit with a Low-Noise and Mismatch-Tolerant Current Mirror Using Chopper Stabilization and Dynamic Element Matching for Electrochemical Sensors

et al. 2021

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This paper presents a potentiostat readout circuit with low-noise and mismatch-tolerant current mirror using chopper stabilization and dynamic element matching (DEM) for electrochemical sensors. Current-mode electrochemical sensors are widely used to detect the blood glucose and viruses in the diagnosis of various diseases such as diabetes, hyperlipidemia, and the H5N1 avian influenza virus (AIV). Low-noise and mismatch-tolerant characteristics are essential for sensing applications that require high reliability and high sensitivity. To achieve these characteristics, a proposed potentiostat readout circuit is implemented using the chopper stabilization scheme and the DEM technique. The proposed potentiostat readout circuit consists of a chopper-stabilized programmable gain transimpedance amplifier (TIA), gain-boosted cascode current mirror, and a control amplifier (CA). The chopper scheme, which is implemented in the TIA and CA, can reduce low frequency noise components, such as 1/f noise, and can obtain low-noise levels. The mismatch offsets of the cascode current mirror can be reduced by the DEM operation. The proposed current-mirror-based potentiostat readout circuit is designed using a standard 0.18 μm CMOS process and can measure the sensor current from 350 nA to 2.8 μA. The input-referred noise integrated from 0.1 Hz to 1 kHz is 21.7 pARMS, and the power consumption was 287.9 μW with a 1.8 V power supply.

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High accuracy potentiostat with wide dynamic range and linearity

Toprak

Vural

Batur

2021

AEU - International Journal of Electronics and Communications

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Low-Noise Integrated Potentiostat for Affinity-Free Protein Detection With 12 nV/rt-Hz at 30 Hz and 1.8 pA^rmsResolution

Cited by 5 publications

References 13 publications

Corroles at work: a small macrocycle for great applications

Corroles at work: a small macrocycle for great applications

A Potentiostat Readout Circuit with a Low-Noise and Mismatch-Tolerant Current Mirror Using Chopper Stabilization and Dynamic Element Matching for Electrochemical Sensors

High accuracy potentiostat with wide dynamic range and linearity

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Low-Noise Integrated Potentiostat for Affinity-Free Protein Detection With 12 nV/rt-Hz at 30 Hz and 1.8 pArmsResolution

Cited by 5 publications

References 13 publications

Corroles at work: a small macrocycle for great applications

Corroles at work: a small macrocycle for great applications

A Potentiostat Readout Circuit with a Low-Noise and Mismatch-Tolerant Current Mirror Using Chopper Stabilization and Dynamic Element Matching for Electrochemical Sensors

High accuracy potentiostat with wide dynamic range and linearity

Contact Info

Product

Resources

About

Low-Noise Integrated Potentiostat for Affinity-Free Protein Detection With 12 nV/rt-Hz at 30 Hz and 1.8 pA^rmsResolution