Low‐pressure airlift fermenter for single cell protein production: II. Continuous culture of pichia yeast

Abstract

Experiments using Pichia yeast grown on n-paraffins have been conducted in laboratory 10-L airlift fermenters and in a 640-L module of commercial scale. Results confirmed the design concept of combining oxygen transfer and fermenter cooling with low-pressure air. However, in the absence of mass transport constraints, the build up of toxic factors in the fermenter appeared to be a major variable limiting cell productivity. Foaming in the large fermenter also presented a serious problem, which must be solved before low-pressure airlift fermenters become practical.

Direct nitrogen stripping and upcycling from anaerobic digestate during conversion of cheese whey into single cell protein

“…Over the end of the previous century, the engineers of the Mobil Research and Development Corporation (United States) developed these reactors up to full commercial modules in the attempt to lower power consumption associated with SCP production from hydrocarbons, i.e. n-paraffins (Chen et al, 1987a;Chen et al, 1987b). These shallow airlift fermenters, having depths below 120 cm, are designed to be supplied with large volumes of low-pressure air, requiring less energy than compressors employed to aerate deeper fermenters.…”

Biotechnological Interventions for Ginsenosides Production

“…The airlift and balloon-type airlift bioreactors are also utilized for ginsenoside production. This type of bioreactors have the additional advantage of better oxygen transfer efficiency with better prediction of flow patterns thus reducing cell shearing [53]. In sprinkle bioreactors, homogeneous culture conditions are usually maintained, and therefore, monitoring becomes much easier [54].…”

High liquid holdup airlift tower loop reactor: I. Riser hydrodynamic characteristics

“…More recently, airlift bioreactors have been used more and more in industry, mainly in the field of biotechnology. They can be used for the cultivation of cells, yeasts or plants;2, 3 for the production of several compounds of biological origin such as alkaloids, antibiotics, proteins, antibodies, etc;4–8 for the elimination of pollutants in emissions from different sources,9, 10 both urban or industrial, through secondary treatment; or for biodegradation of pollutants in the air 11. In the field of chemistry, they are being used to substitute other reactor types, such as mechanical stirred tanks 12…”