Low Prevalence of Antibody to Hepatitis G Virus Among the Risk Groups and Healthy Population of Bangladesh

Abstract

Dr Mahmuda Siddiqua E-mail : mahmuda99@yahoo.com hepatitis, occurring in patients with no other known etiology. 5It is well established that HGV maintains a high and stable level of plasma viremia for many years, 6 which indicates it's efficient and active replication. Before the establishment of antibody detection methods, prevalence rates of HGV RNA in general population varied between less than 1 to 4% in different countries.7 With the development of new tests for detection of anti-HGV antibodies about 3 to 20 % of healthy people are found to have antibodies, indicating that the virus is more widely spread worldwide. In particular, rates of HGV seropositivity have ranged between 2-8% in Asia and North America, between 10-15 % in Europe and around 20% in South Africa and South America.

Seroprevalence of Hepatitis G Virus IgG antibody among blood donors, pregnant women, neonates and apparently healthy population

“…Among the study population in the current study 3 (1.7%) respondents were seropositive for HGV and rest 177 (98.3%) respondents were seronegative for HGV infection. In this regards Siddiqua et al 22 reported the overall prevalence of HGV antibody was 3.2% in a study conducted in Bangabadhu Sheikh Mujib Medical University, Dhaka, which was little high from the present study and may be due to inclusion of commercial sex workers in their study.…”

“…Seropositivity did not differed between male and female (p=0.547). Siddiqua et al 22 found that there was no significant difference seen in their study about the prevalence of HGV between the male (3.2%) and female (3.1%).…”

“…Seropositivity did not differed between previous blood transfusion and no previous blood transfusion (p=0.882). Siddiqua et al 22 reported none of the 62 multiple transfused patients had antibody to HGV. In this study, among the male 2 (2.2%) patients were seropositive for HGV; while in female 1 (1.1%) patient was seropositive for HGV.…”