Low prevalence of atrial fibrillation in asymptomatic adults in Geneva, Switzerland

Schmutz, Mathieu; Beer-Borst, Sigrid; Meiltz, Alexandre; Urban, Philip; Gaspoz, Jean‐Michel; Costanza, Michael C.; Morabia, Alfredo; Zimmermann, Marc

doi:10.1093/europace/eup379

Cited by 22 publications

(21 citation statements)

References 29 publications

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“…Of these, 73 were identified as eligible following review of the title. This was reduced to 13 studies following review of the abstracts [22,23,24,25,26,27,28,29,30,31,32,33,34]. Following methodological assessment of the quality of the full articles, 3 studies were excluded since they did not meet the inclusion criteria [22,24,30], and a further 2 studies were excluded because of low response rates [29,33].…”

Section: Resultsmentioning

confidence: 99%

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The Prevalence, Impact and Economic Implications of Atrial Fibrillation in Stroke: What Progress Has Been Made?

Andrew¹,

Thrift²,

Cadilhac³

2013

Neuroepidemiology

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Atrial fibrillation (AF) is a major risk factor for stroke, especially in the elderly. Increased life expectancies mean that AF-related stroke is a growing global public health concern. Improvements in the detection, treatment and prevention of the consequences of AF have occurred in recent years. However, the extent to which these improvements have impacted on the prevalence of AF, the risk of AF-related stroke and subsequent economic costs are unknown. This review provides a contemporary assessment of the epidemiological data on AF-related stroke aimed at assessing the effectiveness of primary prevention strategies and associated economic implications with reductions in stroke incidence. A systematic review of the literature was performed. Appropriately designed studies were identified and retrieved. Evidence on changes in the prevalence of AF, the risk of stroke associated with AF and the excess cost of AF-related stroke over the last 30 years was summarised. The results provide evidence that the age-adjusted prevalence of AF and the relative risk of stroke associated with AF has remained relatively constant. Unless action is taken to improve detection of AF and reduce its consequences, a considerable increase in the social and economic burden associated with AF-related stroke is likely.

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Section: Resultsmentioning

confidence: 99%

“…Consequently, there was a slightly greater prevalence rate of AF in that study than in those where only ECG was used to diagnose cases. Between 41 and 72% of AF cases detected in these studies were asymptomatic [28,31,32]. …”

Section: Resultsmentioning

confidence: 99%

The Prevalence, Impact and Economic Implications of Atrial Fibrillation in Stroke: What Progress Has Been Made?

Andrew¹,

Thrift²,

Cadilhac³

2013

Neuroepidemiology

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“…It exists a wide range of uncertainty [20,[32][33][34] around the AF studies design. It is well known that AF prevalence is considerably higher in hospitalized patients especially in internal medicine and geriatric wards (31% for patients ≥70-year-old) [35] than in primary care [36][37][38].…”

Section: Discussionmentioning

confidence: 99%

Diagnosed, undiagnosed and overall atrial fibrillation research on population over 60 year-old. AFABE study

Clúa-Espuny¹,

Princep²,

Roso-Llorach³

et al. 2014

Cardio Vasc Syst

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Background: Undiagnosed atrial fibrillation usually is only detected with the first complication. We estimated undiagnosed Atrial Fibrillation prevalence, overall AF and associated factors in a public health-service area in Catalonia, north-eastern Spain. Methods: Multicentre, cross-sectional study, with people randomly selected among the attended population over 60 years old by primary care teams regardless of follow-up time in health centres or at homes. Information was collected through ECGs, electronic medical history reviews and medical interviews. Descriptive and logistic regression analysis was performed. Results: 1043 subjects were recruited (47.1% male), mean age: 73.1 y-o (SD: 7.8 y-o); 43.3% ≥75-year-old. Overall AF prevalence was 10.9% (CI95% 9.1-12.8%); higher in men than in women, progressively increasing with age (24.4% in ≥85-year-old). Only women ≥85-year-old had higher prevalence (26.2%) than men (22.5%). Undiagnosed AF relative prevalence was 2.2% (IC95% 1.3-3.1%). These results show that about 1 in 50 people over 60 years old could suffer undiagnosed AF. The higher risk of AF undiagnosed was found in: men (OR 2.5 IC95% 1.0-6.2), >75 years old (OR 2.5 IC95% 1.0-6.1), heart failure history , who live in rural areas (OR 15.9 IC95% 1.5-160.1) and to whom no one ECG was performed in the last two years. Conclusions: The overall AF prevalence increased 10 times from the sixties to over eighties and the proportion man-woman changes from 4:1 to 1:1. The undiagnosed AF prevalence was 2.2% (IC95% 1.3-3.1). This percentage should be added to the one of untreated cases with OAC.

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“…Sin embargo, en la població n general se observa un importante desconocimiento sobre esta enfermedad, y a pesar de que el tratamiento antitrombó tico puede reducir las complicaciones embó licas, han sido muy pocas las campañ as de diagnó stico precoz en nuestro medio. Se estima que la FA está presente en un 0,5-1,2% de la població n, aunque puede llegar a un 10% de los sujetos de má s de 70 añ os [1][2][3][4][5] . En el estudio PREV-ICTUS, realizado en Españ a 6 , la prevalencia de FA segú n aná lisis de la historia clínica y electrocardiograma de 7.108 sujetos de 60 o má s añ os fue del 8,5% (el 4,2% de 60-64 añ os y el 16,5% en los mayores de 84 añ os).…”

Section: Introducció Nunclassified

Una campaña de información y diagnóstico de la fibrilación auricular: la «Semana del Pulso»

Sanmartín

Fraga²,

Martín-Santos

et al. 2013

Revista Española de Cardiología

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Low prevalence of atrial fibrillation in asymptomatic adults in Geneva, Switzerland

Abstract: This population-based survey of a general Swiss population indicates that the prevalence of AF remains below 1%. These results are less alarming than those from previous studies based on patients seeking medical care.

Cited by 22 publications

References 29 publications

The Prevalence, Impact and Economic Implications of Atrial Fibrillation in Stroke: What Progress Has Been Made?

The Prevalence, Impact and Economic Implications of Atrial Fibrillation in Stroke: What Progress Has Been Made?

Diagnosed, undiagnosed and overall atrial fibrillation research on population over 60 year-old. AFABE study

Una campaña de información y diagnóstico de la fibrilación auricular: la «Semana del Pulso»

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