Conducting polymers (CPs), the so-called "fourth generation of polymeric materials", can solve essential problems in biosensing technologies due to their unique material properties and implementation in innovative device systems. CPs have excellent biocompatibility. They can provide advantageous interfaces for bioelectrodes owing to their hybrid conducting mechanics, combining both electron and ionic charge carriers. Many (i.e. glucose) biosensors use immobilized enzymes to form a selective layer on CP structure. Miniaturization of sensors is a new requirement. Mini sensors are portable and wearable with low utilization of sample and cost-effective technology of production.