“…It is noteworthy that some molecular regulators of neutrophil apoptosis, such as CD69, SAA, and SHP, are practically not detectable in healthy people, but their count increases dramatically in some diseases. At the same time, increased CD69 and SAA expression is associated with suppression of apoptosis [ 91 , 96 , 97 ], while SHP, on the contrary, with its activation [ 76 , 46 ] ( Table 1 ). Local tissue lesions associated with acute circulatory disorders or trauma is the cause of the development of sterile inflammation accompanied by DAMP release and neutrophilic infiltration.…”