Lower Limb Amputations in Southern Finland in 2000 and Trends up to 2001

Abstract

There was a reduction in the number of amputations in Southern Finland during the past 17 years. This occurred synchronously with the increase in vascular reconstructions. Our data suggests that vascular surgery saves patients from BK-amputations and therefore relative amount of AK-amputations inevitably rises.

Differences in characteristics between people with lower limb amputations who died before 12 weeks and those who survived: Short Report

“…Poor preoperative mobility and low preoperative BI scores are predic tors of death (Leung and Wong, 2004 (2000), Eskelinen et al (2004), Leung and Wong (2004). Eskelinen et al (2004) reported 29% deaths in 30 days, but the mean age was 72 years, 10 years older than those in this study. Papazafiropoulou et al (2009) only reported such findings at one to two year post operatively and, their participants were also 10 years older.…”

“…Mortality rates of 12%, and 29%, at one week, and 30 days respectively have also been reported (Eskelinen et al, 2004). Back Pettersson and Bjorkelund (2005) reported that, one third of parti cipants died within six months regard less of gender and age.…”

Global trends in incidence of lower limb amputation: a review of the literature

“…Diabetic complications (neuropathic foot and ischemic foot), peripheral vascular disease (PVD), trauma, malignancy, infection and congenital lower limb defects have been seen to result in LLA, at varying rates (Engstrom et al 1993;Van Houtum et al 1996;Spinchler et al 2001;Wong 2005;Global Lower Extremity Study 2000). Eskelinen et al (2004) also reported that burns, rhabdomyolysis, sepsis and cellulitis can lead to LLA. Geographical site, male gender, duration of diabetes, presence of co-morbidities, and lack of high school education is associated with the high incidence of LLA (Wrobel et al 2001;, Wong et al 2005.…”

Plasmid-based gene therapy of diabetes mellitus

“…This condition is responsible for 70% of the lower limb amputations. 73 Although a combination of neuropathy, obstructive macrovascular disease and/or microvascular changes is usually pivotal in the development of the diabetic foot, the contribution of microvascular occlusions is predominant in the diabetic subgroup with CLI and is not accessible for surgical revascularization. 74,75 The median survival of patients with CLI is approximately 3 years.…”