&lt;i&gt;Tribolium confusum&lt;/i&gt; (Confused Flour Beetle, Rice Flour Beetle) – An Occupational Allergen in Bakers: Demonstration of IgE Antibodies

Schultze‐Werninghaus, G.; Zachgo, Wolfgang; Rotermund, H.; Wiewrodt, Rainer; Merget, R.; Wahl, R.; Burow, G.; Strassen, Richard Zur

doi:10.1159/000235407

Cited by 20 publications

(12 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Likewise, among 133 bakers tested by skin prick, 8.3% were positive to T. confusum (228). Schultze-Werninghaus and colleagues later reported that IgE in the sera of subjects exposed to rye and wheat flour bound to three T. confusum-specific proteins (229).…”

Section: Confused Flour Beetlesmentioning

confidence: 99%

Arthropod Allergens and Human Health

Arlian

2002

Annu. Rev. Entomol.

157

114

View full text Add to dashboard Cite

Many species of arthropods are the sources of potent allergens that sensitize and induce IgE-mediated allergic reactions in humans. Most of these arthropod allergens are proteins, and the allergic response mechanism to these allergens is the same as it is for allergens from other sources such as plant pollens, molds, and foods. Aside from ingestion of crustaceans (shrimp, lobster), among arthropods, humans have the greatest contact with insects and mites, and as a result allergies to these two groups of arthropods have been the most frequently reported. Because of the large number of people affected by allergic reactions to stinging insects, cockroaches, and dust mites, many allergens of these organisms have been extensively studied, purified, and immunobiochemically characterized and for some recombinant allergens, produced. Cocktails of these recombinant allergens have the potential for use in diagnosis and immunotherapy. In this chapter, we review the insects and mites that induce allergic reactions. Where the information exists, the immunobiochemical characterization of the allergens and the frequency of sensitivity or clinical reactivity in the human population are also reviewed. As background, the beginning of this review includes sections that define allergens, explain the allergic reaction mechanism, and describe the methods for naming allergens.

show abstract

Section: Confused Flour Beetlesmentioning

confidence: 99%

Arthropod Allergens and Human Health

Arlian

2002

Annu. Rev. Entomol.

157

114

View full text Add to dashboard Cite

show abstract

“…There are a few reports of IgE-mediated respiratory allergy to confused flour beetle [51][52][53][54]. Among the 1,040 patients with perennial asthma and/or rhinitis and with proven sensitization to indoor allergens, 16.5% had positive skin prick tests and 30.7% positive intradermal tests to whole-body extracts of T. confusum [51].…”

Section: Confused Flour Beetlementioning

confidence: 99%

“…Among the 1,040 patients with perennial asthma and/or rhinitis and with proven sensitization to indoor allergens, 16.5% had positive skin prick tests and 30.7% positive intradermal tests to whole-body extracts of T. confusum [51]. Positive skin prick test was also noted in 8.3% of 133 bakers [52], and specific IgE to T. confusum proteins was detected in 9 of 125 sera of subjects exposed to rye and wheat flour [53]. A case of IgE-mediated respiratory and skin allergy as a result of occupational exposure to T. confusum has been reported recently [54].…”

Section: Confused Flour Beetlementioning

confidence: 99%

Allergy to Miscellaneous Household Arthropods

Kim¹,

Hong²

2007

PPL

View full text Add to dashboard Cite

Of the various arthropods, humans have the greatest contact with mites and cockroaches, and as a result, allergies to these two groups have been the most frequently reported. Changes in lifestyle and living environment have encouraged the growth of arthropods other than mites and cockroaches, and consequently, human exposure to antigens derived from the new arthropods has increased. Although systematic approaches to and immunobiochemical studies of these arthropods are relatively sparse compared with those of mites and cockroaches, recent reports have shown that many species of household arthropods can elicit IgE-mediated reactions via inhalation, biting, or stinging. In this chapter, we review the other arthropods that can induce allergic reaction to human beings. Where the information exists, the frequency of sensitivity and clinical manifestation, and the characterization of the allergens are also reviewed. Virtually all species of arthropods may be sources of allergens that can sensitize and induce IgE-mediated allergic reactions in humans.

show abstract

“…Different allergens including storage mites (4), flour beetles and moths cause occupational asthma in bakers (5) and workers exposed to grains (6,7). This study reports the presence of Bla g 2 allergen, derived from German cockroach, in flour samples.…”

mentioning

confidence: 99%