<p>Adherence to Anti-Tuberculosis Treatment Among Pediatric Patients at Nekemte Specialized Hospital, Western Ethiopia</p>

Abstract

Background Non-adherence to tuberculosis treatment is the most challenging and hindering factor for successful tuberculosis therapy. The long duration of tuberculosis treatment and the undesirable effects of anti-tuberculosis drugs result in non-adherence to treatment among pediatric patients. Hence, this study was aimed to evaluate pediatrics adherence status among tuberculosis pediatric patients on anti-tuberculosis treatment at Nekemte Specialized Hospital. Methods A health facility-based cross-sectional study design was used to recruit pediatric TB patients who were receiving their treatment between February 15 and March 15, 2019. Adherence to tuberculosis therapy was evaluated using data obtained from face-to-face interviews of their respective caregivers. The collected data were entered into EPI-manager 4.0.2 software and analyzed using SPSS version 24. Logistic regression was used to analyze the variables and variables with p-value <0.05 had a statistically significant association with the adherence to anti TB treatment. Results Among 202 participants involved in the study, 120 (59.4%) of them were males and 119 (58.9%) were in the age category of 11–15 years. A total of 166 (82.2%) of the patients had extra-pulmonary tuberculosis and 174 (86.1%) of them were in the intensive phase. Of the pediatric tuberculosis patients, 48 (73.3%) of them have adhered to the treatment regimen. Female gender [AOR: 3.3, 95% CI: 1.52–7.2], younger age (0–5 years) [AOR: 5.96 95% CI: 1.81–19.6], living in urban area [AOR: 3.73, 95% CI: 1.67–8.36], and patients who did not experience side effect [AOR: 2.87, 95% CI: 1.41–5.81] were predictors of good adherence to tuberculosis treatment up on multivariable logistic regression analysis. Conclusion The level of adherence observed in our study area was low. Age, sex, residence, and side effect experience showed an association with tuberculosis treatment adherence. Therefore, health care providers should educate all patients with tuberculosis before the initiation of anti-tuberculosis treatment.

A cross sectional study on factors influencing non-adherence to treatment among paediatric tuberculosis patients in field practice area of Osmania Medical College, Hyderabad

“…Similar findings were seen in study done by did not experience side effect were significant predictors. 5 Similar findings were seen in study done by Bagchi et al 6 In another study done by Santos et al showed that the majority of patients were compliant (63.9%). 7 Noncompliance was found in 36.1%.…”

Clinical standards for drug-susceptible pulmonary TB

“…Health education should be age-specific, gender-sensitive, delivered in the patient’s own language and address potential challenges for the caregiver when administering medication. 77 – 80 Health education is essential for PTB treatment adherence and for ensuring safety by improving patients’ understanding of risks and benefits and providing clear instructions for reporting adherence challenges and adverse events, thereby motivating treatment completion. 72 Patients need to know when to contact the healthcare provider in the event of symptoms suggestive of adverse effects.…”

Hubungan Pengetahuan terhadap Tingkat Kepatuhan Pasien Tuberkulosis Paru di Puskesmas Binangun Cilacap

“…Pengetahuan yang dimiliki pasien menjadi salah satu faktor yang dapat mempengaruhi terjadinya kegagalan terapi selain peran pengawas minum obat, dukungan keluarga, akses transportasi dan jarak dari tempat tinggal pasien menuju tempat pelayanan kesehatan, motivasi dan efek samping yang dirasakan 3,4 . Kepatuhan diartikan sebagai tingkatan seseorang dalam berperilaku untuk memperoleh keberhasilan pengobatan, diet dan melakukan gaya hidup yang sesuai dengan rekomendasi dari pelayanan kesehatan 5,6 . Kepatuhan merupakan suatu gambaran perilaku yang terbentuk karena adanya interaksi dari petugas kesehatan dengan penerima terapi atau pasien agar pasien dapat mengerti rencana dan konsekuensi dari langkah yang diambil serta menyetujui hasil perencanaan dan melaksanakannya 7,8 .…”