2020
DOI: 10.2147/cia.s257166
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<p>Comparison of OSTA, FRAX and BMI for Predicting Postmenopausal Osteoporosis in a Han Population in Beijing: A Cross Sectional Study</p>

Abstract: Purpose: To validate the efficacies of three screening tools including the Osteoporosis Self-Assessment Tool for Asians (OSTA), Fracture Risk Assessment Tool (FRAX) without bone mineral density (BMD), and body mass index (BMI) for predicting postmenopausal osteoporosis (OP) and to define the ideal thresholds for avoidance of dual-energy X-ray absorptiometry (DXA) scanning in a Han Chinese population in Beijing. Patients and Methods: A total of 2055 community-dwelling Han Beijing postmenopausal females aged ≥45… Show more

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Cited by 27 publications
(21 citation statements)
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“…To investigate the accuracy of OSTA and OSTC in osteoporosis prediction, WHO criteria were applied as the reference standard for the diagnosis of osteoporosis at anatomical sites. While OSTA has been widely assessed in Asia [ 16 , 32 , 35 , 37 41 ], evidence for OSTC is still limited. In our study, the validity of two tools was assessed for different sites, with the results obtained for femoral necks being better than those for lumbar vertebrae.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…To investigate the accuracy of OSTA and OSTC in osteoporosis prediction, WHO criteria were applied as the reference standard for the diagnosis of osteoporosis at anatomical sites. While OSTA has been widely assessed in Asia [ 16 , 32 , 35 , 37 41 ], evidence for OSTC is still limited. In our study, the validity of two tools was assessed for different sites, with the results obtained for femoral necks being better than those for lumbar vertebrae.…”
Section: Discussionmentioning
confidence: 99%
“…Another self-assessment tool, FRAX, which was published by Kanis in 2010 [ 19 ], has a declared accuracy equivalent to OSTA in the present study for the detection of osteoporosis. However, for femoral necks, OSTA performs better, with AUC values ranging from 80.0% to 85.8% [ 16 , 35 , 41 ], and is even comparable with other tools that use more complicated modeling [ 42 ]. OSTC also revealed good results for the lumbar vertebrae, with minimum and maximum AUC values of 68.7% and 71.6%, while recording better results for femoral necks with AUC values from 80.5% to 86.4%.…”
Section: Discussionmentioning
confidence: 99%
“…These results are in contradiction to our study. On the other hand, a study of Wright N.C reported 10.3% prevelance among 50 years old) population of United States 11 . Osteoporosis is challenging issue in many regions of the world due to significant morbidity ratio ad socio-economic burden 12 .…”
Section: Discussionmentioning
confidence: 91%
“…(2) Patients had the clinical manifestations with spontaneous pain in the whole body, waist, thorax, and back. (3) The BMD in patients measured by dual-energy absorptiometry was lower than 2.5 standard deviations below the mean in healthy people of the same age and sex. (4) Patients had not taken any drugs affecting the bone metabolism in the last three months.…”
Section: Inclusion and Exclusionmentioning
confidence: 91%
“…The incidence of fractures significantly increases [ 1 , 2 ], which seriously affects the patients' quality of life. In recent years, with the aggravation of the population aging in China, the incidence of osteoporosis has increased, and the relevant data predict that the number of patients with osteoporotic fractures will reach 6 million by 2050 in China with the corresponding medical expenditure more than RMB 100 billion [ 3 , 4 ]. Therefore, the deepening of clinical research on osteoporosis is beneficial for reducing the future medical burden in China and improving the prognosis of elderly patients with osteoporosis.…”
Section: Introductionmentioning
confidence: 99%